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The cases and control subjects respectively were chosen as cases and control subjects respectively, 110 pregnant women with vitamin B12 deficiency and carrying fetuses with CHD and carrying fetus fetuses with CHD. An elevated risk of an offspring with CHD was found in the present study, as well as cases with GA genotype, A allele under the prevalent and allelic models respectively, and cases with AA genotype under the co-dominant and recessive models. Moreover, though Homocysteine levels in GA and AA genotypes of the CUBN G253A variant were elevated, it was discovered that all CHD case mothers were vitamin B12 deficient irrespective of the CUBN genotype.
Source link: https://zenodo.org/record/5875779
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