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Metabolic disorder - U.S. Department of Veterans Affairs

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Last Updated: 23 April 2022

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Positron emission tomography assessment of cerebral glucose metabolic rates in autism spectrum disorder and schizophrenia.

Several models have been developed to account for observed overlaps in clinical appearance and genetic predisposition to schizophrenia and autism spectrum disorder. In the frontal lobe, anterior cingulate, superior temporal gyrus, amygdala, and medial thalamic nuclei, metabolic rates in schizophrenia patients were reduced compared to controls; in the occipital cortex, basal ganglia, and lateral thalamic nuclei were reduced in comparison to controls; metabolic rates in schizophrenia subjects were reduced in the occipital cortex, hippocampus, basal gd In comparison to controls, subjects with ASD and schizophrenia showed contradictory metabolic rates in the primary motor and somatosensory cortex, anterior cingulate, and hypothalamus; in prefrontal and occipital cortices, inferior parietal lobule, amygdala, hippocampus, and basal ganglia. Schizophrenia and ASD seem to be closely linked to a similar pattern of metabolic abnormalities in the social brain.

Source link: https://doi.org/10.1007/s11682-017-9721-z

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions