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Metabolic - Crossref

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Last Updated: 15 May 2022

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Patterns of Lifestyle Behaviors and Relevant Metabolic Profiles in Chinese Adults: Latent Class Analysis from Two Independent Surveys in Urban and Rural Populations

Background: This was determined to establish the characteristics of lifestyle habits and their relationships with metabolic profiles in Chinese urban and rural adults. Methods: This was a cross-sectional survey carried out in the Nanjing and Hefei Community Cardiovascular Risk Surveys from 2011-2013, using random cluster sampling. The patterns of physical activity in Chinese urban and rural populations as well as the metabolic profile in each pattern were discovered by latent class analysis. For example, the most common cluster was found to have a long night nap sleep cycle, a long sitting time, and above WHO recommended physical fitness for both walking and MOVPA, while the smallest cluster was highlighted due to its large number of MOVPA and limited amount of walking. Between the two survey sites, there was a difference in the proportion of each cluster was discovered. Conclusion: Common lifestyle behaviour clusters were outlined, which led to a better understanding of people's daily habits.

Source link: https://doi.org/10.18502/ijph.v51i5.9423


Consequences of AphanizomenonFlos-aquae(AFA) extract (Stemtech TM ) on metabolic profile of patients with type 2 diabetes

Abstract Background Blue-green algae is one of the most nutrient dense foods that are abundant in nutrients with beneficial effects on human health. The aim of this research was to determine the effectiveness of a water-soluble extract of the cyanophyta Aphanizomenon Flos-aquae as a functional supplement to CD markers, lipid profile, glucose levels, as well as its side effects in Iranian patients with type 2 diabetes. After each meal for a period of 12 weeks, the StemFlo capsules were given one capsule of StemFlo before breakfast and two capsules of StemEnhance after each meal for a period of 12 weeks, and the placebo group was instructed to take placebo with the same pattern. Conclusion Solemtech's intervention resulted in improved blood glucose levels in Iranian patients with type 2 diabetes, and has subsequently recommended the Stemtech TM as a diabetic food for diabetes management.

Source link: https://doi.org/10.1186/s40200-015-0177-7


The interaction between stress and metabolic disruption in student population – preliminary study

Abstract Introduction: About 26% of people aged 18 to 24, respectively, are overweight or obese, and the number of people with elevated body mass index is on the rise. The study was conducted to investigate the connection between psychological stress and body composition in the student population. Methods and methods: The study team consisted of 80 students aged 19 to 28 years old from Lublin's universities. Using the Persuad Stress Scale, the severity of stress conditions was determined. Although 60% of people had elevated stress levels, 60 percent of people had elevated stress levels. Individuals with high stress were characterized by lower: TBW, ECF, and ICF expressed in liters, and less FFM represented in kilograms. Conclusions: To prevent negative changes in ant hropometric measurements, psychological instability, and student health, implement appropriate healt h education services should be considered.

Source link: https://doi.org/10.2478/cpp-2021-0022


Yaobishu Regulates Inflammatory, Metabolic, Autophagic, and Apoptosis Pathways to Attenuate Lumbar Disc Herniation

We wanted to investigate Yaobishu's key mechanisms of lumbar disc herniation here. palmitic acid target genes mainly control the PPAR signaling pathway, Ras signaling pathway, and fat acid metabolism, according to a KEGG review. Using autologous nucleus pulposus tissue implantation, the rat LDH model was created. By RNA-Seq, differential expression gene related to metabolism, inflammation, autophagy, and apoptosis in the control and LDH groups' dorsal root ganglion tissue samples was tested. To develop an in vitro LDH model, TNF- stimulated DRG neuronal cells were used to develop an in vitro LDH model. According to Pearson's correlation report, DCN was positively linked to BCL2A1, indicating that autophagy may be negatively related to apoptosis in LDH. The RNA-Seq results revealed that YBS downregulated S100A9 and CTSW expression, while upregulating SOCS3, CDKN1A, UHRF1, LEPR, and BCL2A1 expression. Our findings may have the theoretical and experimental basis for clinical trials of LDH disease treatment in clinical trials.

Source link: https://doi.org/10.1155/2022/3861380


Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome

Following pandemic influenza H1N1 infection, there have been strong correlations between elevated body mass index, type-2-diabetes, and an elevated risk of hospitalization. Similarly, a correlation between elevated blood glucose level and SARS-CoV-2 infection severity and death has been identified, indicating MetS as a key predictor of clinical outcomes in patients with COVID-19 patients. In response to physical fitness, skeletal muscle hormones, called myokines, which have been released in response to physical activity, can influence both metabolic homeostasis and immune system function. This paper seeks to summarize new findings in the field of exercise immunology, including the acute and chronic effects of exercise on myokines production and immune system function, as well as immune system function.

Source link: https://doi.org/10.3390/nu14102054


Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis

Astaxanthin has positive results in reducing MetS risk, according to the risk of MetS, although individual studies are inconclusive. This systematic review summarizes the latest available astaxanthin research in adults with MetS risk factors. In 14 electronic databases from inception to 2021, a systematic search of English and Chinese randomized controlled trials in 14 electronic databases was conducted. Astaxanthin's marginal effect on lowering total cholesterol and systolic blood pressure has been negligible, as shown by marginal results, as well as a significant attenuating effect on low-density lipoprotein cholesterol. Astaxanthin's effects in adults with MetS are limited by more detailed studies.

Source link: https://doi.org/10.3390/nu14102050


RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence

Abstract Background Stem cell senescence is considered a key factor of organismic aging. In comparison to that obtained from young rats by performing RNA sequence, we found 868 up-regulated and 2006 down-regulated differentially expressed genes in bone marrow mesenchymal stem cells from old rats in comparison to those from young rats. The results showed that the high number of DEGs could play a role in cell differentiation, growth factor binding, and etc. , while the down-regulated DEGs were largely enriched in metabolism processes, such as cell differentiation, metabolic process, and mitochondria. We screened and confirmed DEGs related to glucose metabolism and determined glycolysis levels in the glycolysis samples, based on the results of then. To clarify the potential molecular mechanisms of glucose metabolism that affects MSC senescence, we performed microRNA analysis on the key DEGs of glycolysis, which was more important. In age-associated MSC senescence, we also established DEGs relating to glucose metabolism and down-regulated glycolysis level.

Source link: https://doi.org/10.1186/s13578-022-00796-5


Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome in Women: Effects of Lifestyle Modifications

Non-alcoholic fatty liver disease is the most common liver disease, characterized by fatty acids liver accumulation and subsequent fibrosis. NAFLD prevalence varies from 80% to 90% in obese patients and is estimated to be around half in patients with metabolic syndrome. Ultrasound has played a leading role in the diagnosis and follow-up of fatty liver disease recently. The elastic and mechanical characteristics of liver tissue are determined by Shear wave elastosonography. Thirty-two female subjects with metabolic syndrome were subjected to medical, anthropometric, and laboratory evaluations, as well as abdominal ultrasonographic/elastosonographic data collected from enrollment time and after 3 months of lifestyle changes. T1's laboratory results showed significant reductions in total and LDL cholesterol, triglycerides, basal blood glucose, 120 min glycaemia, basal insulin, and HOMA Index. At T1 for steatosis degree and elastosonographic results, a similar change was observed. The size of the liver positively correlated with body mass, BMI, neck and waist circumferences, waist to height ratio, insulin and HOMA Index, body mass, and visceral fat, and steatosis grade, according to the linear regression analysis of baseline conditions. With more variables and with greater statistical sensitivity at T1 relative to T0, the degree of steatosis was positively correlated with greater precision and greater statistical value. The positive correlations between the degree of steatosis and neck circumference, HOMA Index, and triglycerides seemed to be highly significant. Women with metabolic syndrome should be focusing on lifestyle changes rather than NAFLD's intervention.

Source link: https://doi.org/10.3390/jcm11102759


Metabolic Syndrome and Male Fertility: Beyond Heart Consequences of a Complex Cardiometabolic Endocrinopathy

Both male infertility and homosexuality accounts for approximately half of cases of couple infertility around the world. The current comprehensive report aims to address male infertility and MetS' pathophysiological causes, as well as the latest available research into MetS' reproductive consequences.

Source link: https://doi.org/10.3390/ijms23105497

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions