Medical Diagnosis - Springer Nature

Frequency and predictors of unspecific medical diagnoses in the emergency department: a prospective observational study

"As a result, the ED diagnosis at hospital admissions can often be a descriptive disease," u201cdecreased general condition"u201d. Patients with such unspecific ED diagnosis differ from patients with a specific ED diagnosis and if they have a poor outcome, according to our aim. Methods We conducted a prospective observational study in Bern university hospital in Switzerland for all adult non-trauma patients admitted to any internal medicine ward from August 15th to December 7th, 2015. Patients receiving unspecific diagnosis at ED discharge were more likely to be women with a non-specific complaint, less often on antibiotics, and less often on antibiotics. Women and patients with non-specific presenting symptoms and no abnormal heart rhythm are at risk of receiving unspecific ED diagnoses that do not allow for targeted diagnosis, discharge, or prognosis. ".

Source link: https://doi.org/10.1186/s12873-022-00665-x

Receptor-mediated cascade targeting strategies for the application to medical diagnoses and therapeutics of glioma

"The special anatomical structure of the brain, in particular, the bloodu2013brain barrier and the bloodu2013brain tumor barrier," says the drug delivery rate is limited, and it leads to drug delivery failures for many drugs. In this research, we summarize the receptors and targeting ligands used in glioma, the types of RMCT designs, and the nanoplatforms used in RMCT methodologies. We hope that the RMCT plans would provide a reference for glioma therapy in the clinic and improve patient quality with glioma. ".

Source link: https://doi.org/10.1007/s11051-022-05482-8

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