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Malaria - Astrophysics Data System

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Last Updated: 15 August 2022

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Bifurcation Analysis of Multiscale Malaria Model with Serratia AS1 Bacteria and Saturated Treatment

Serratia AS1 bacteria effectively inhibit P. falciparum growth in mosquito populations, and quickly disseminate by mosquito-to-mokoraine. In this paper, we introduce a new malaria model to investigate the role of saturated treatment and AS1 bacteria in malaria transmission. Human and mosquito populations dynamics vary on a variety of temporal scales, according to one of the models. Finally, the model without AS1 bacteria transmission is used to simulate Burundi's accumulative malaria cases.

Source link: https://ui.adsabs.harvard.edu/abs/2022IJBC...3250134W/abstract


The effect of climate change on malaria transmission in the southeast of Iran

From 2000 to 2019, Zahedan district's daily malaria prevalence estimates were obtained. To find the right combination of parameters for nonlinear modeling, the gamma test was used. ANN Simulated the impact of climate change on malaria transmission in 2021-2060. According to the current model, the future climate in Zahedan district will be warmer, more humid, and with more precipitation. ANN's report in Zahedan under both conditions showed the number of malaria cases in the case of climate change on the incidence of malaria. The daily malaria reports from 2013 to 2019 were used only for initial analysis due to a lack of daily malaria data before 2013, and in preprocessing and simulation analyses, the daily malaria results from 2013 to 2019 were used. Therefore, if proper measures are not implemented, malaria will remain a health problem in this region.

Source link: https://ui.adsabs.harvard.edu/abs/2022IJBm...66.1613N/abstract


PfHRP2 detection using plasmonic optical fibers: a step towards early malaria diagnosis

Low concentrations of analytes can be detected by biosensing using optical fibers. We devised a cost-effective fiber-based solution to check the presence of Plasmodium falciparum histidine-rich protein 2, a biomarker for malaria diagnosis, in this region. Unclad multimode optical fiber probes are coated with a thin gold film to excite Surface Plasmon Resonance, offering excellent sensitivity to the surrounding medium and more specific to target-bioreceptor interactions in this work. Anti-PfHRP2 antibodies on gold and its passivation enabled precise detection in various media types of media. In a sandwich assay, we used secondary antibodies as amplifiers, which allowed us to increase the method's sensitivity. To improve the surface selectivity, different blocking agents were tested. PfHRP2 was first measured using spiked proteins in phosphate buffer saline and then tested in vitro using new Plasmodium falciparum strains.

Source link: https://ui.adsabs.harvard.edu/abs/2022SPIE12139E..0QL/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions