Advanced searches left 3/3

Lysosomal Storage Disorders - Crossref

Summarized by Plex Scholar
Last Updated: 02 April 2022

* If you want to update the article please login/register

Establishment of Cutoff Values for Newborn Screening of Six Lysosomal Storage Disorders by Tandem Mass Spectrometry

In this report, we used MS/MS to screen for LSDs and found an appropriate way to determine the cutoff value for LSD screening in this research. Methods The experimental results were evaluated with MassLynx V4. 1 in six Chinese province hospitals, including Jinan, Dezhou, Heze, Linyi, Weifang, and Zibo; The total number of 38,945 samples from newborn blood tablets from various maternity hospitals in six cities in Shandong province, including Jinan, Dezhou, Heze, Linyi, Weifang, and Zibo; In every test, the laboratory used 30% of the median GLA enzyme production and 20% of the median ABG, ASM, GALC, IDUA, and GAA enzyme activities, as the cutoff values for that batch of experiments was determined. The ambient temperature could be a reason why the enzyme activity cutoff value has seasonal variations.

Source link: https://doi.org/10.3389/fped.2022.814461

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions