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Lymph Nodes - Springer Nature

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Last Updated: 26 September 2022

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Melanocytic nevi in sentinel lymph nodes: association with cutaneous nevi and clinical relevance in patients with cutaneous melanomas

Purpose Melanocytic nevi in lymph nodes is a crucial histological difference between the initial sentinel lymph node metastasis in melanoma. In 1,250 patients with SN biopsy for melanoma, we wanted to associate NN in SNs with clinicopathologic signs and survival rates. With increasing SN metastasis diameter, we observed a decreasing NN prevalence. Parents with more than 50 cutaneous nevi were also highly affected by melanoma patients with more than 50% cutaneous nevi. Conclusions We found a strong correlation between NN diagnosis and multiple cutaneous nevi, as well as providing circumstantial evidence that cutaneous nevi in lymph nodes is particularly relevant. The trend toward lower melanoma-specific survival in SN-negative patients with NN indicates that careful differentiation of SN metastases is crucial.

Source link: https://doi.org/10.1007/s00432-021-03894-y


Prognostic value and management of regional lymph nodes in locoregional breast cancer recurrence: a systematic review of the literature

The purpose of this study was varied. Methods The repeat sentinel node biopsy procedure was performed as a repeat sentinel node biopsy procedure was performed, providing national and international guidelines, as well as a systematic review of the literature between Jan 1, 1999 and Feb 1, 2021. Positive regional lymph nodes in recurrent breast cancer have a poorer outcome, with axillary recurrences being the most common tumor site among all nodal regions. PET-CT, scintimammography, and SPECT-CT can help pinpoint lymph nodes outside of the axilla. Conclusions Prognostic value of a non-symptomatic disease diagnosis has prognostic value. The selection of surgical care of clinically inapparent regional lymph nodes during local recurrence should be based on the previous nodal staging technique. Patients with previous ALND should be saved a second systemic ALND.

Source link: https://doi.org/10.1007/s00404-021-06352-9


Deep learning combined with radiomics for the classification of enlarged cervical lymph nodes

Purpose: The application of deep learning alongside conventional radiomics techniques for classifying enlarged cervical lymph nodes is investigated. Methods 276 patients with enlarged cervical lymph nodes who were hospitalized from January 2015 to January 2021 were retrospectively reviewed, with medical and computed tomography imaging results. The radiomics features were extracted using one-by-one convolution and neural network activation, filtered with the least absolute shrinkage and selection operator model, and used to create a discrimination map for PyTorch. Results A total accuracy of 87. 5 percent was established by a research model containing five common radiomic functions and 97 deep learning elements, which were selected with LASSO and used to develop a discrimination model. Conclusions in the classification of cervical enlarged lymph nodes using CT-based deep learning in conjunction with standard radiomics techniques has a high diagnostic value.

Source link: https://doi.org/10.1007/s00432-022-04047-5


Immunosuppressive properties of human PD-1 + , PDL-1 + and CD80 + dendritic cells from lymph nodes aspirates of lung cancer patients

DCs in lung cancer have immunomodulatory properties, and it is of concern. During the EBUS/TBNA treatment of 29 patients with primary lung cancer, LNs aspirates were obtained. In the metastatic LNs and the PB, we saw a larger percentage of DCs in the metastatic than in the non-metastatic LNs and the PB. In the metastatic LNs, the proportions of PD-1 +, PD-L1+, and CD80 + DCs was higher than those in the non-metastatic ones. DCs cells have increased expression of PD-1, PD-L1, and CD80 molecules that can associate with T lymphocytes, according to this study.

Source link: https://doi.org/10.1007/s00262-022-03178-5


The awareness of radiologists for the presence of lateral lymph nodes in patients with locally advanced rectal cancer: a single-centre, retrospective cohort study

Goals Enlarged lateral lymph nodes have been attributed to increased local recurrence rates. In MRI reports in a tertiary referral center, the aim was to see how often LLNs are mentioned in MRI reports. Methods Anorectal Junction Methods A single center, retrospective review of 202 patients treated for primary rectal cancer between 2012 and 2020, with at least a T2 tumor located within 12cm of the anorectal junction. The radiology papers were authored by 30-u201340 consultant radiologists, who were in charge of the 30’su201340 radiology studies. In 89 cases, the presence or absence of LLNs was confirmed by the primary MRI studies. LLNs and other pertinent characteristics of those LLNs were seldom reported in primary MRI surveys. Only 44% of primary MRI reports mentioned LLNs and relevant characteristics of those LLNs. U2022 Comprehensive reporting of lateral lymph nodes in primary MRI studies was limited to less than half. u2022 Ly nodes in posterior multidisciplinary meetings or listed in restaging studies are not always discussed.

Source link: https://doi.org/10.1007/s00330-022-08840-1


Optimal settings of near-infrared fluorescence imaging with indocyanine green for intraoperative detection of lymph node metastasis in esophageal cancer

Indocyanine green has been used for intraoperative diagnosis of lymph node metastasis in several cancers. We present a new NIR-guided surgical method for predicting lymph node stations potentially carrying LNM in EC with high diagnostic accuracy derived from precisely setting the ICG injection setting.

Source link: https://doi.org/10.1007/s11748-022-01859-7


A new technique for robotic lateral pelvic lymph node dissection for advanced low rectal cancer with emphasis on en bloc resection and inferior vesical vessel preservation

Background Lateral pelvic lymph node dissection is becoming more important in the treatment of advanced low rectal cancer patients. Herein, we describe a new method for robotic lateral pelvic lymph node dissection for advanced low rectal cancer with an emphasis on en bloc resection and inferior vesical vessel preservation. Methods Robotic LPLN dissection was performed in 12 consecutive patients between April 2020 and December 2021. The ureterohypogastric nerve fascia, vesicohypogastric fascia, and internal obturator muscles were used in anatomical landmarks during the Fascia-oriented LPLN dissection of the internal iliac region and obturator region. Eight patients were male and the median patient age was 62 years old, with eight patients being female. Conclusions A new method for robotic LPLN dissection for advanced low rectal cancer with emphasis on en bloc resection and inferior vesical vessel preservation can be safely performed, making it a promising surgical procedure.

Source link: https://doi.org/10.1007/s00464-022-09275-x


Supraclavicular and Contralateral Axillary Lymph Node Involvement in Breast Cancer Patients

Patients with contralateral axillary disease treated with curative intent are more like patients with ipsilateral supraclavicular disease and other locally advanced breast cancers than patients with de novo distant metastases elsewhere. Some argue in favor of reclassifying contralateral axillary metastases from Stage IV to Stage III breast cancer with no distant metastasis, which is similar to ipsilateral supraclavicular metastases.

Source link: https://doi.org/10.1245/s10434-022-12134-7


Sentinel lymph node biopsy at robotic-assisted hysterectomy for atypical hyperplasia and endometrial cancer

Endometrial cancer diagnosis by Lymph node is contentious. A complete pelvic lymph node biopsy reduces the likelihood of a complete nodal biopsy while minimizing the risks of a complete pelvic lymph node dissection. Whether you're looking for a unique hyperplasia or endometrial cancer patient undergoing robotic-assisted hysterectomy (SLNB or PLND) will be investigated; to determine the use, convenience, and role of SLNB to determine their peri-operative findings; and compare their peri-operative findings. The RAH u00b1 LN assessment for endometrial cancer or AH was conducted from December 2018 to February 2021 among women who underwent RAH b1 LN assessments for endometrial cancer or AH. In the SLNB cohort, there was a statistically shorter length of stay, less estimated blood loss, and shorter surgical duration compared to the no LN assessment group. In the SLNB, there was statistically significant less estimated blood loss and surgical duration in the SLNB relative to the PLND cohort.

Source link: https://doi.org/10.1007/s11701-021-01321-5

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions