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Left Ventricular Assist Devices are auxiliary pumps that facilitate pumping from the failure left ventricle. Using Lagrangian tracking in a moving-wall ventricle flow simulation, we investigate the possibility of activation and aggregation of platelets in the left ventricle caused by altered hemodynamics. Despite having their origins at various injection times, platelet trajectory reports revealed a series of platelets that remained together for extremely long times. The remarkably long residence time in the LV, as well as its close proximity to other activated platelets, could help determine the presence of LVAD-induced LV hemodynamics that cause the hazy danger of thrombosis.
LVADs have become a common therapy for advanced heart failure patients in the last decade. This research investigates the effect of flow patterns of the synchronicity of the pulsatility mode with the LV contraction cycle. PIV measurements were conducted in an LV silicone model implanted with an LVAD, resulting in 3C-2D velocity fields. This speed modulation achieved a significant effect on LVAD flow rate, with lower minimums present at the time when the modulation occurred during LV relaxation.
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