Advanced searches left 3/3

Long COVID - Europe PMC

Summarized by Plex Scholar
Last Updated: 07 April 2022

* If you want to update the article please login/register

Case Report: Therapeutic and immunomodulatory effects of plasmapheresis in long-haul COVID

Patients with COVID-19 experience a variety of debilitating signs months after being infected, including a condition called long-lived COVID. The patient returned to regular activities and work following two rounds of therapeutic plasma exchange. In the patient's peripheral blood mononuclear cells, the patient's peripheral blood mononuclear cells' markers of inflammation macrophages were reduced, and lymphocyte markers, including natural killer cells and cytotoxic CD8 T-cells, increased.

Source link: https://europepmc.org/article/PPR/PPR478097


Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort.

About 10% of people infected with severe acute respiratory syndrome coronavirus 2 have symptoms of post COVID-19 disease. We collected results from 968 adult patients with a confirmed infection enroled in the ComPaRe long COVID cohort, a disease-aware prospective cohort of such patients in France. Patients' responses to the Long COVID Symptom Tool, a validated self-reported questionnaire assessing 53 signs, were determined by day-by-day prevalence of post COVID-19 signs. Patients who have been sick for 2 months, 85% have continued symptoms one year after their symptom onset.

Source link: https://europepmc.org/article/MED/35383197


Survival After Severe COVID-19: Long-Term Outcomes of Patients Admitted to an Intensive Care Unit.

Objection To determine long-term outcomes of patients who needed intensive care unit admission for severe COVID-19. Patients with severe COV19 related to an ICU admission in a two-hospital academic health center in Southern California have been invited to an ICU. This is a prospective cohort study of patients with severe COVD-19 requiring an ICU admission in a two-hospital academic health system. Patients discharged alive between 3/21/20/20 and 12/31/2020 were surveyed about six months after discharge to determine health-related quality of life using Patient-Reported Outcomes Measurement System v1. 1, post-traumatic stress disorder, and loneliness scales, with patient-Reported Outcomes Measurement Information System (29. 20), post-traumatic stress disorder, and loneliness scales. Patients were also questioned about receiving invasive ICU care. 305 patients admitted to the ICU for severe COVID-19, 205 were discharged alive, and 132 completed surveys were conducted a median of 182 days post-discharge. Conclusions Based on the 6 months post-discharge, patients with severe COVID-19 have good results, with health scores comparable to the general population.

Source link: https://europepmc.org/article/MED/35382627


Serological Biomarkers at Hospital Admission Are Not Related to Long-Term Post-COVID Fatigue and Dyspnea in COVID-19 Survivors.

Methods A cohort study was done in one urban hospital of Madrid during the first wave of the outbreak, including patients hospitalized due to COVID-19. At 6 months and 56. 6 percent and 13. 6% at 12 months after hospital discharge, respectively, there was a 72 percent and 17. 2% prevalence of post-COVID exhaustion and dyspnea. Patients with post-COVID exhaustion lasted longer than expected, had a lower hemoglobin, elevated lymphocyte count, and lower neutrophil and platelet counts, whereas those experiencing post-COVID dyspnea at 6 or 12 months had lower platelet count, lower neutrophil, and platelets counts, respectively, than those not experiencing post-COVID dyspnea or dyspnea. Conclusion In patients with post-COVID exhaustion or dyspnea, the patients' post-COVID symptoms were slightly different, but they were unable to explain the patient's long-COVID disorders.

Source link: https://europepmc.org/article/MED/35381597


Healthcare-Associated Infections in Veterans Affairs Acute and Long-Term Healthcare Facilities During the Coronavirus Disease 2019 (COVID-19) Pandemic.

Mission: To determine the effect of the coronavirus disease 2019 pandemic on healthcare-associated infections reported from 128 acute care and 132 long-term care Veterans Affairs facilities, according to a Department of Veterans Affairs. Results In January 2021, the nationwide VA COVID-19 admissions reached their high point. During the pandemic period in acute care facilities, significant rises in the incidence of CLABSIs, VAEs, and MRSA all-site HAIs were recorded. There was no significant change in CAUTI rates, although C. difficile rates significantly decreased. There were no significant rises in HAIs in long-term care facilities. Conclusions and Conclusions The COVID-19 pandemic had a different effect on HAIs of various types of VA acute care, with some rates increasing. The minimal effect of COVID-19 in VA long-term facilities may represent differences in patient numbers and acuity, as well as early knowledge of the pandemic's effects on nursing home residents, leading to increased awareness and analysis of infection prevention and control practices in this setting.

Source link: https://europepmc.org/article/MED/35379366


Long term impact of the COVID-19 associated AKI: the relationship between kidney recovery and mortality in a 10-month follow-up cohort study.

Introduction In the previous literature, Corona Virus-2019-associated acute kidney injury and its short and mid-term effects on kidneys has been well documented, indicating a large number of AKI in hospitalized patients with high mortality risks, as well as high rates of unsolved kidney disease at the time of discharge, as well as high mortality rates. Methods In this cohort research, patients hospitalized with COVID-19 who survived to the discharge were followed for a median of 9. 6 months. Following adjustment for potential confounders, Cox regression revealed that AKI stage 3 and unresolved kidney disease at the time of discharge were strongly correlated with mortality during the post-discharge period. Even after hospitalization for a long time, it was found that patients with COVID-19, mainly stage 2 and 3, and patients with unsolved kidney disease at the time of discharge were at a higher risk of death, particularly after hospitalization for an extended period.

Source link: https://europepmc.org/article/MED/35378541


Cardiac impairment in Long Covid 1-year post-SARS-CoV-2 infection

Long-Covid is a film about multiple organs and diseases. We investigated the 12-month course of cardiac disease in people with Long Covid using cardiac magnetic resonance. Methods 534 people with Long Covid underwent baseline CMR and multi-organ MRI at six months after the first post-COVID-19 signs were identified at baseline, and 330 people were retested at 12. 6 months if abnormal results were reported at baseline. The impairment was characterized as one or two of: low left or right ventricular ejection fraction, high left or right ventricular end diastolic volume, low 3D left ventricular global longitudinal strain, or elevated native T1 in 3 cardiac segments. At baseline, 52/534 [19%] had cardiac disease at baseline; 71/102 had complete paired results at 12 months, with 141/534 [19%] experiencing heart disease at 12 months. The results of CMR findings, symptoms, or clinical outcomes were not predictive of CMR findings, diseases, or clinical outcomes of cardiac troponin I and B-type natriuretic peptide.

Source link: https://europepmc.org/article/PPR/PPR476989


Histopathology of Persistent Long COVID Toe: A Case Report.

For nearly 22 months, a 59-year-old obese man with a suspected COVID-19 cause severe cyanosis with histopathologic capillary thrombosis of toes. First exposure to papillary dermal capillary thrombosis, telangiectasia, and peri-ecchyti lymphocytic infiltrates resembling pernio. Biopsy of the distal toe, 16 weeks after initial exposure to papillary dermal capillary thrombosis with endothelial swelling, telangiectasia, and peri-eccrine lympho This is the first case of biopsy of "long COVID toe" following a suspect SARS-Cov-2 infection, with reports of thrombotic vasculopathy, toe cyanosis, and pernio-like pathology.

Source link: https://europepmc.org/article/MED/35366017


Long-term psychological consequences of long Covid: a propensity score matching analysis comparing trajectories of depression and anxiety symptoms before and after contracting long Covid vs short Covid

Aims (forte): investigating whether psychological signs first emerged after SARS-CoV-2 infection, as well as long-term traces of psychological dysfunction comparing long and short Covid groups. Using growth curve modelling, they were matched to participants who had short Covid using propensity score matching on a variety of demographic, socioeconomic, and health covariates and health covariates. Both long and short Covid groups's inflammation rates show that depressive and anxiety symptoms were immediately related to the onset of infection. But the long-Covid group had noticeably higher initial rises in depressive symptoms and elevated levels in elevated levels over a 22-month follow-up. Initial anxiety rises were not significant between groups, but only the brief Covid group experienced an increase in fear over the follow-up, contributing to widening gaps between groups. Conclusions The results were published in a journal that published research on the psychobiological pathways involved in the onset of psychological disorders related to long Covid.

Source link: https://europepmc.org/article/PPR/PPR476765

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions