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Long COVID - ClinicalTrials.gov

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Last Updated: 07 April 2022

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Long COVID: Evaluation of Physical and Functional Status

The patient who has suffered from COVID-19 and whose signs and symptoms have been present for 12 weeks since its diagnosis. Participants in the non-recruited sampling method of probabilistic convenience will be recruited. The results will be analyzed by statisticians using the statistical software International Business Machines Statistical Package for the Social Sciences 27. The relationship between categorical variables will be reviewed using percentages and relative frequencies. The Chi-square test or Fisher's exact measure will be used to determine categorical variables' potential association. We will use Spearman's correlation coefficient to determine the potential relationship between ordinal categorical variables in order to determine Spearman's correlation coefficient. Numeric variables are categorized by means of the mean and standard deviation, as well as the interquartile range, depending on whether or not the normality condition of the results is satisfied. Depending on whether or not the data normality condition is determined, the student's T test or the non-parametric U-Mann Whitney test will be used to compare the means of two independent samples. Depending on whether or not the normality condition of the data is established, the one-way ANOVA procedure or the non-parametric Kruskal Wallis test will be used in the case of means of three or more independent samples. The comparison of Pearson correlation coefficients helps to determine the possible correlation between the numerical variables, which may indicate a positive correlation. According to the goals and the associations that could be found, it is likely to use other statistical software or even suggest the creation of mathematical models predictive.

Source link: https://clinicaltrials.gov/ct2/show/NCT05228691


LOng COvid COmorbidities: Evaluation of Endocrine, Metabolic, Neuropsychiatric, Muscle, Cardiovascular, Pulmonary and Dermatologic Functions

The investigation into the potential muscle damage will include fatigue, reduced resistance, and muscle endurance, reduced muscle endurance, reduced muscle endurance, improved exercise tolerance, and myopathy. The investigation into the potential cardiological harm will include echocardiographic changes at rest and during echocardiogram stress tests, as well as cardiovascular dysfunctions.

Source link: https://clinicaltrials.gov/ct2/show/NCT05293366


Burden of Care of Long COVID Patients After Hospital Discharge

3. 5 million people have been affected by SARS-COV2 in France since March 2020, and over 250 000 patients have been hospitalized and safely discharged. Currently, the French epidemiological situation shows a steady and high incidence of new cases of COVID-19 and associated hospitalizations. In most cases, the disease's progression is favorable, but patients with a mild disease may have "Long-COPVID" syndrome, a patient-created condition that can persist for weeks or months beyond the initial signs. Chronic disease of this post-COVID chronic illness is often described as "long COVID. " Although the evidence is still scarce, patients who have been hospitalized for COVID19 may be at a greater risk of long-coviD. We recommend focusing on hospitalized and discharged COVID-19 patients with persistent symptoms in order to determine their healthcare resource use and corresponding costs, as well as comparing them to patients not experiencing the long-CoviD version of the disease. The aim of this research is to determine whether various patterns of long-COVID healthcare intake can be identified.

Source link: https://clinicaltrials.gov/ct2/show/NCT05073328


ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan

This brings the gap between acute care of COVID-19 and outpatient therapy or rehabilitation of post-/long-COVID patients. Standard care currently diagnoses post-/long-COVID-19 syndrome and makes recommendations for treatment by primary care clinics and specialty outpatient clinics. Post-COVID outpatient clinics are mainly located in metropolitan areas and are therefore primarily available to patients in large cities. In particular, young people who have no to no prior outpatient care due to a very simple course do not receive primary care and many do not have primary care and, in fact, may not have primary care and may not have the knowledge of the specific condition, delayed and ineffective medical assistance. What screening system can reliably identify patients suffering from post/long-COVID syndrome? With this initiative, several researchers and the general public will be investigated, as well as the following research questions and hypotheses, which will be reported to the various stakeholders and the general public: What screening device can reliably detect patients suffering from post/long-COVID syndrome? What does it look like for patients with post/long-COVID syndrome? How can an interdisciplinary health care pathway look like in the long run? Hypothesis: An interdisciplinary treatment path should guide the patient, with the support of a consultant, in such a way that the patient obtains quickly and effectively recovers from his or her post-CoVID disease, improves his or herself's function, reduces incapacity to work, and regains participation.

Source link: https://clinicaltrials.gov/ct2/show/NCT05238415


Symptoms and Biomarkers of Long COVID-19 in People Living With and Without HIV

This is a prospective observational research being carried out to find out about the late effects of COVID-19 in people with and without HIV. The investigators intend to do this by looking at people with COVID-19 and people who haven't had COVID-19, as well as those who have HIV and people who are HIV-negative, among others. The investigators will look at the average duration of symptoms after COVID-19, how these diseases influence quality of life, and what medical conditions are common post COVID-19 in people with and without HIV. Participation involves: Participant-based surveys about themselves, their health history, their quality of life, and mood in the recent past, as well as information about COVID-19 or HIV if the participant has a history of either disease.

Source link: https://clinicaltrials.gov/ct2/show/NCT04958889


Yale COVID-19 Recovery Vaccine Study: Measuring Changes in Long Covid Symptoms After Vaccination

The Yale research team's REDCap at Yale will deliver survey results and alerts to survey participants, and specimen collection coordination will be coordinated between the Yale research team and Yale's New Haven Health draw sites. During a phone call, a research coordinator will read a script designed to alert the participant of the study's design and risks in order to ensure that the participant understands the research before consent. If the participant has any questions for the study coordinator, the participant will also be asked if the participant has any questions for the study coordinator. At any of the study's two Yale New Haven Health blood draw sites, participants will test blood and saliva samples three times. Although all specimen collection will be carried out in Connecticut, people who are not currently patients within Yale New Haven Health will also be eligible to participate in the study, as long as the participant is willing and able to travel to one of the blood draw locations 3 times. The Yale research permission would include consenting to providing blood and saliva samples three times at a Yale New Haven Health site. Survivor Corps is a nonprofit group of people who lived long-term effects of SARS-CoV-2 infection and sought to gather data about people with extended recovery. Patient-Led Research is also an autonomous group of individuals who suffered long-term SARS-CoV-2 disease and want to collect data about people with prolonged recoveries.

Source link: https://clinicaltrials.gov/ct2/show/NCT04895189


Obstructive Sleep Apnea in Patients With Long COVID-19 Fatigue: a Multicentre Prospective Cohort Study

The most common post-COVID-19 symptom has been fatigue symptoms up to 6-7 months after acute COVID-19 disease, which is related to myalgic encephalomyelitis/chronic fatigue syndrome, has been identified as the most common post-COVID-19 symptom. Patients in the post-COVID-19 Outpatient Clinics will be able to determine the prevalence of OSA and its association with post-COVID-19 exhaustion, which has been present for at least six months after the acute disease. Demographic, clinical, and clinical research forms will be collected between the 6-7th month after the diagnosis of COVID-19 and 9 months later. ESS - The evaluation of OSA-related daytime sleepiness will be determined using the Epworth Sleepiness Scale - ESS. Between the diagnosis of COVID-19 and the OSA's diagnosis, the OSA diagnosis will be performed using a portable monitoring device model III.

Source link: https://clinicaltrials.gov/ct2/show/NCT05290350


Safety and Tolerability of Full Spectrum Cannabidiol Dominant Medicinal Cannabis in Treating Symptoms Associated With Long COVID: A Feasibility Study

Long COVID's symptoms and continuing care have been getting more popular, especially through the establishment of separate treatment units within the NHS. Although the signs and severity of Long COVID may vary greatly between individuals, several of Long COVID's common signs include exhaustion, breathlessness, insomnia, sleep disorders, and dysautonomia. This evidence shows that CBD may be a safe treatment for people with Long COVID. Our research will determine whether it is feasible to recruit and keep patients with a diagnosis of Long COVID into a clinical trial of a CBD dominant medical cannabis. Our results will show whether medicinal cannabis is safe to use in the treatment of Long COVID and whether it is safe to use.

Source link: https://clinicaltrials.gov/ct2/show/NCT04997395


Better Understanding Physical and Cognitive Impairments and Functional Limitations in People Suffering From Long COVID to Support the Development of Adapted Interventions

People with long COVID, b people with physical and cognitive impairments and functional limitations, as well as others with long-term COVID, b people with long COVID, who obtained self-reported and objective clinical data, and c people with chronic illness and high functioning were compared over time, including those with long COVID, b people with long-serving symptoms, and c people with chronic illness and functional limitations, and c people with chronic illness and persistent symptoms and a Two hundred and twenty adults with long COVID signs Long COVID syndrome Long COVID were diagnosed with long COVID (19) and 120 age-and-match adults who did not sign COVID-19, but did not experience persistent symptoms, according to one hundred and twenty adults who did not sign COVID-19, 120 age- and sex-matched adults who did not attend COVID-19, but did not experience persistent symptoms. Acute COVID Group and 120 age-and- ANOVA for repeated measures will be used to compare longitudinal results between groups in self-reported and clinical variables. Long COVID patients' physical, cognitive, and functional limitations, as well as health-related quality of life, are still being established, and providing prompt medical and rehabilitation services to people suffering from long COVID are still being common, and long-term physical and cognitive impairments and functional limitations can contribute to improved outcomes such as long-term physical and cognitive impairments, as well as health-related quality of life.

Source link: https://clinicaltrials.gov/ct2/show/NCT05216536

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions