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Legionnairesu2019 disease is a more serious disease characterized by pneumonia and is related to bacteria of the genus Legionella" (including a non-pneumonic influenza-like syndrome). Legionellosis is becoming more popular as a public health issue around the world; although it is underreported disease, studies have consistently shown a high incidence. Legionnaires'u2019 disease diagnosis is mainly based on the detection of Legionella pneumophila serogroup 1 antigen in urine. Legionella spp. lab tests were run to determine Legionella spp. A shorter prognosis has been attributed to ineffective or late antibiotic therapy in Legionella pneumonia. The majority of published studies evaluating antibiotic therapy for Legionnaires'u2019 disease are observational and thusly vulnerable to bias and confounding. "Well-designed studies are needed to determine the accuracy of diagnostic tests regarding clinical outcomes, as well as random studies comparing fluoroquinolones and macrolides, as well as randomized trials comparing fluoroquinolones and macrolides or mixed therapies that assess outcomes and adverse events. ".
Source link: https://doi.org/10.1007/s40121-022-00635-7
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