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Lead Poisoning - Europe PMC

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Last Updated: 16 January 2022

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Selenium Alleviated Oxidative Stress-Mediated Complex Poisoning Mechanism in Lead-Treated Chicken Kidneys: Inflammation, Heat Shock Response, and Autophagy

It's also known that selenium has an antagonistic effect on Pb poisoning. The aim of this investigation was to identify the Pb poisoning mechanism in chicken kidneys by oxidative stress, inflammation, heat shock response, and autophagy. One hundred and eighty male Hyline chickens were randomly divided into the control group, the Pb group, and the Pb+Se group. Pb-induced oxidative stress, inflammation, heat shock response, autophagy, and Se administration reduced Pb poisoning by minimizing oxidative stress in the chicken kidneys.

Source link: https://europepmc.org/article/PPR/PPR428337


Louis Tanquerel des Planches (1810-1862) and the history of discovering lead poisoning in the nervous system.

We only left with one significant medical research, Louis Tanquerel des Planches' Traité des maladies de plomb ou saturnines, which first appeared in 1839, which was published in 1839. Throughout the second half of the nineteenth century, the work served as a blueprint for diagnosing and treating lead poisoning. Lead poisoning was considered lead poisoning by most physicians and two millennia, i. e. Tanquerel found seventy-two reports of harm to the central nervous system in workers exposed to lead in Parisian workshops, including paroxysms of abdominal pain. He investigated their workplaces and unambiguously disclosed the deplorable conditions that caused so many patients to die after having no reservations about walking away from La Charité Hospital, where he had treated patients with lead poisoning. Tanquerel demonstrated lead in brain tissue and consequently showed neurological toxicity as early as 1839, with support from chemists and pharmacists.

Source link: https://europepmc.org/article/MED/34776262

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions