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ABSTRACT Background: SARS-CoV-2-induced inflammation in COVID-19 is triggered by cytotoxic and pro-oxidant interactions that potentiate alveolar, endothelial, and immune tissue damage. In comparison to D-dimer, lactic acid, and interleukin-6 as markers of endothelial injury and inflammation process, we investigated the effect of medicinal ozone administration on the oxidative stress markers. Methodology: In vivo and in vitro, medicinal ozone containing oligo metals was used to determine the quantities of: H 2 O 2, NO, GPx, TAP, TBARs, D-dimer, lactic acid, and interleukin-6. Both in vitro and in vivo, a medical ozone treatment with oligo metals induced changes in oxidative stress markers. The H 2 O 2 and TBARs levels decreased, in turn, NO figures increased. On the other hand, the antioxidant enzyme levels in the antioxidant enzyme system slightly increase, suggesting an antioxidant enzyme control that counteracts the infection's pro-oxidative effect. Conclusion: The medicinal ozone treatment has a decrease in the markers of oxidative stress, inflammation, and cell death, as well as cell synthesis, and cell death, as well as decreasing plaque aggregation, which contribute to decreased risk of vascular endothelial disease. These services may be able to be integrated into the treatment of endothelial disease in COVID-19 patients. Finalmente is a zón del tctico y d'mero-D, estableciendo una mejora del metabolismo y de la función endotelial respectivamente, per seguido y de la función endotelial.
Source link: https://zenodo.org/record/6464527
Both vanadium and lactic acid, respectively, were found to be of first order in terms of kinetics of oxidation of lactic acid by quinquecent vanadium. The Arrhenius equation has been found to be correct for reactions between 25° and 35°.
Source link: https://zenodo.org/record/6507692
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