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For minimizing its low melting property and slow crystallization rate, we suggested a green approach to incorporate biodegradable cellulose nanofibers into the PLA matrix. CNFs in the PLA matrix were obtained by a combination of acetylation surface modification and melt-compounding techniques, resulting in well-dispersed hydrophobic-modified CNFs. Compared to the plain PLA, the PLA/CNF composites had significantly improved crystallization capabilities and melt elasticity. The ready PLA/CNF nanocomposite foams had the largest expansion ratio at 1. 5 MPa under ultralow pressure at 1. 5 MPa.
Source link: https://europepmc.org/article/MED/IND607694081
Following heating to 95°C, a cheese from milk adjusted to pH 6. 2 using CO2 had a marginally reduced total Ca content, a lower melting temperature, and less labor to stretch to 38 cm. According to a larger decrease in total Ca content, higher moisture content, and decreases in cheese firmness, melting temperature, and work to stretch, we reduced milk pH to 6. 2 using lactic acid.
Source link: https://europepmc.org/article/MED/IND607672250
Public health and the global economy are increasingly worried about antibiotic resistance. The lactic acid bacteria that produce dairy products and are often present in the agro-zoootechnical environment may act as reservoirs of antibiotic resistance genes, acquiring or transporting them to other microorganisms. Commercial strains of Lactobacillus, Streptococcus, and Bifidobacterium commonly used for industrial dairy products are often intolerant to gentamycin, kanamycin, chloramphenicol together with tetracycline. As a result of global limits on the use of antibiotics in animal husbandry, the presence of resistant wild LAB in raw milk products has drastically reduced.
Source link: https://europepmc.org/article/MED/IND607671962
In 6 h in TSB, the results of the study revealed that 5% and 10% postbiotics + EDTA reduced the number of L. monocytogenes by nearly 5. 0 log10 in TSB. On day 0, the chicken drumstick decontaminated with 10% PA was found as 2. 1 log10 lower than the control group, but not 10% lower than the control group. In the chicken drumstick decontaminated with 10% Postbiotics+1% LA groups, the L. monocytogenes counts in the chicken drumstick decontaminated with 10% Postbiotics+1% LA groups were found to be 1. 1 log10 lower than the control group. In the 10% Postbiotics+1% LA samples, the lowest total mesophilic aerobic bacteria counts in the chicken drumsticks were found, but postbiotics did not alter the drumstick samples' color, and no postbiotics changed the drumstick samples' color characteristics. In conclusion, biobiotics and their blends with natural preservatives could be a promising alternative to reduce the food-borne pathogens and meat products' shelf life.
Source link: https://europepmc.org/article/MED/IND607663954
Human intestinal flora is extremely diverse, with lactic acid bacteria living as part of the most essential gut microbes that improve host health. In the case of probiotic and bacteriocin respectively, the use of lactic acid bacteria as a whole organism or its metabolite is extensive. Hence, the desire to always bio-prospect for newer strains of lactic acid bacteria is vital. Both isolates have the ability to produce lactic acid from glucose, while their tolerance to pH 3 and salt levels varied widely, at 2%, 4%, and 6. 5%. Traditional fermented foods such as kunun-zaki and kindirmo, as well as probiotic analysis, starter culture, and probiotic research were all found to be a good source of lactic acid bacteria for product creation, starter culture, and probiotic research.
Source link: https://europepmc.org/article/PPR/PPR490608
Commensal bacteria play a key role in many skin functions by providing the first layer of protection against pathogens and retaining the skin barrier. Although the skin microbiome benefits of glycerol are well documented, our study shows the overall benefits of glycerol on the skin microbiome, while showing an alternate mode of action of glycerol for several skin health benefits.
Source link: https://europepmc.org/article/MED/35535416
Despite androgen depletion therapy, castration-resistant prostate cancer with sustained androgen receptor signaling remains a significant medical issue. The Jumonji C-containing histone lysine demethylase family four members, KDM4A, are primary coactivators of AR to promote prostate cancer tumor formation and are potential treatment targets for CRPC patients with AR mutations/changes-mediated resistance. The cytotoxic effects of myricetin on various prostate cancer cells was compared. The combined therapy, PLGA-myricetin, enzalutamide, and enzalutamide, had significantly higher antitumor activity than that of the control group in the C4-2B xenograft model, with enhanced antitumor function. Tumor growth was much lower for the combination therapy than for enzalutamide or myricetin therapy alone. Conclusions: Myricetin is a pan-KDM4 inhibitor and demonstrated potent cell cytotoxicity toward CRPC cells, according to these results.
Source link: https://europepmc.org/article/MED/35534851
In this way, the filter performance of particular matter and the pressure drop were dramatically enhanced in the prepared PLA/DFs NFMs relative to the simple PLA NFM. In addition, the PLA/DFs5 NFMs' yield strength and crystallinity percentage had soared from 1. 88 Mpa and 27. 7% to 2. 72 Mpa and 32 percent, which was quite impressive. Following those unique characteristics, the PLA/DFs5 demonstrated outstanding degradability, which was followed by the degradation of 38% in 0. 01 M sodium hydroxide solution after 7 days and about 100% in natural condition after 42 days, respectively. Meanwhile, the environmentally friendly raw materials of the composite polylactic acid and artificially cultured diatom frustules could be extracted from corn-derived biomass and artificially cultured diatoms, ensuring the conformance to carbon freeness and promising applications in personal protection.
Source link: https://europepmc.org/article/MED/PMC9073818
Following treatment with CurNisNps, quantitative real-time polymerase chain reaction measured the expression of the virulence-factor-related genes of S. mutans and C. albicans. Acrylic resin specimens without CurNisNps were found to exhibit flexural failure in comparison with acrylic resin specimens without CurNisNps as the control group. CurNisNps and flexural strength value were both simultaneously accepted and experimentally accepted curNisNps. According to S. mutans and C. albicans, the anti-biofilm and anti-metabolic activity of acrylic resin specimens with a 5% content of CurNisNps could significantly reduce the expression levels of gtfB and HWP in S. mutans and C. albicans. Conclusions Our results show that 5% of CurNisNps would act as an excellent orthodontic acrylic resin additive against S. mutans and C. albicans biofilm with no adverse effects on its mechanical properties.
Source link: https://europepmc.org/article/MED/35524235
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