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LAD - Europe PMC

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Last Updated: 07 April 2022

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Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging.

After permanent or transient ligation of the left anterior descending artery, we investigated the connection between 18F-FDG derived left ventricular metabolic volume, defect region, and cardiac function in mice. The loss of LVMV correlated with the defect area identified by QPS software. After permanent and transient LAD ligation, permanent and transient LAD ligation, the QGS software's cardiac function parameters positively correlate with LVMV. This report provides new insight into 18F-FDG-derived LVMV after permanent and transient LAD ligation by longitudinal in 18F-FDG PET imaging, and highlights the correlations of the FDG derived parameter and cardiac function.

Source link: https://europepmc.org/article/MED/35355159


Detection of cardiac apoptosis by [ 18 F]ML-10 in a mouse model of permanent LAD ligation.

Purpose The absence of viable cardiac cells and cell death by myocardial infarction is also a significant barrier in preventing heart disease from deteriorating heart failure. After permanent ligation of the left anterior descending artery resulting in myocardial infarction, apoptosis in murine hearts was seen in autoradiography and positron emission tomography. [18 F]MML-10 is in accordance with the defect visualized by [18 F]FDG and the histological approach, with the detection of apoptosis by [18 F]FDG and the histological approach. [18 F]ML-10 may be a good tracer for apoptosis imaging in a mouse model of permanent LAD ligation.

Source link: https://europepmc.org/article/MED/35352214


Predicting Values of Neutrophil-to-Lymphocyte Ratio (NLR), High-Sensitivity C-Reactive Protein (hs-CRP), and Left Atrial Diameter (LAD) in Patients with Nonvalvular Atrial Fibrillation Recurrence After Radiofrequency Ablation.

BACKGROUND IN a post-RFA study, the aim of this research was to determine the predictive values of lipid level, inflammatory biomarkers, and echocardiographic parameters in late NVAF recurrence following RFA. METHODS AND MATERIAL DESIGN METHODS This multi-center research recruited 263 patients with paroxysmal or persistent NVAF who underwent initial RFA from Jan 2017 to Jan 2019. For determining the predictive factors of late NVAF recurrence, Univariate and multivariate logistic regression analyses were used. Receiver operating characteristic curves were developed to determine the predictive ability and the ideal cut-off rate of variables. RESULTS Late NVAF recurrence in 70 patients after the initial RFA within a 12-month follow-up. Patients in the Recurrent cohort had significant higher NLR, hs-CRP, LVEDD, LVESD, and LAD than those in the Nonrecurrent group. CONCLUSIONS The combination of preoperative NLR, hs-CRP, and LAD can help anticipate late NVAF recurrence.

Source link: https://europepmc.org/article/MED/35082255

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions