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Source link: https://doi.org/10.46570/utjms.vol6-2019-331
"Abstract Background and Purpose Randomized controlled trials have challenged the belief that reperfusion results after mechanical thrombectomy may vary depending on the retrieval methods used; however, new reports have shown that acute ischemic stroke patients with susceptibility vessel sign may respond differently. We wanted to compare different stent retriever-based thrombectomy procedures with respect to interventional outcome parameters based on SVS status. 240 patients were treated with a combination of SR and distal aspiration, while 204 patients were treated with a first-line thrombectomy. Regardless of SVS status, the results show no superiority of any specific SR-based retrieval method, despite previous reports that suggested higher rates of reperfusion than contact aspiration in AIS patients with SVS.
Source link: https://doi.org/10.1007/s00062-021-01079-1
"Abstract Purpose The purpose of this essay "Abstract Purpose" is a description that can be used to detect the entire spectrum of pathology by deviations from a learned model. We investigated the use of a poorly managed ML device to discover characteristic findings related to ischemic stroke in head CT and subsequent patient triage. Patients admitted to a tertiary care hospital in April 2020 with either no anomalies, subacute or chronic ischemia, lacunar infarcts of the deep white matter, or hypervascular signs were retrospectively assessed. During the investigation period, 208 patients were referred to head CT of which 111 could be included. AUC to distinguish normal from pathological scans was 0. 98 95% CI 0. 97. 01-20131. 00 Conclusions Our review found that a weakly supervised anomaly-detection device could be used to detect stroke findings in head CT. In > 23% of patients, the definitive classification into normal/pathological was achieved with high accuracy.
Source link: https://doi.org/10.1007/s00062-021-01081-7
"Methods: Patients with head and neck cancer aged 20-to-2016 were registered from 2007 to 2016 in the Taiwan Cancer Registry from 2007 to 2016. We compared the risk of stroke in patients with head and neck cancer who underwent radiotherapy or surgery alone. In patients with head and neck cancer, the overall SIR of stroke was 1. 37 in comparison to the general population. The completely adjusted HR of stroke in patients with head and neck cancer was 0. 96 percent, compared to those who did not receive radiotherapy alone. Patients with head and neck cancer were at a greater risk of fatal or non-fatal ischemic stroke. In patients first treated with radiotherapy, the risk of stroke was not elevated. "Ethicists should emphasize stroke prevention in all patients with head and neck cancer, not just in those who have radiotherapy. ".
Source link: https://doi.org/10.1158/1055-9965.epi-21-0753
"We found that the serum total bilirubin level and the direct bilirubin level were positively related to the severity of ischemic stroke. " The direct bilirubin level was linearly related to stroke severity, and the increase in the possibility of mild or severe ischemic stroke may have been attributed to the 1% rise in the likelihood of having moderate or severe ischemic stroke. Patients with ischemic stroke have high bilirubin levels, and they may be a measure of initial oxidative stress.
Source link: https://doi.org/10.3390/jcm11123262
"Hemorrhage repair is the most feared complication of intravenous thrombolysis in acute ischemic stroke. " After IVT, we invented and tested various machine learning algorithms, with the ability of predicting HT in AIS. Within 48 h after IVT, the forty-five patients had HT within 48 hours. According to the ROC curve results, the AUCs of HT predicted by the RF model, LR model, MSS, SITS, and SEDAN scales after IVT were 0. 655, 0. 655, and 0. 655, respectively. The RF model was more effective than those models and scales that were available. The RF prediction model was made clinically interpretable by the SHapley Additive exPlanation results. After intravenous alteplase, the sensitivity was 66. 7 percent, and specificity was 80 percent," this review revealed, an RF machine learning technique was successfully developed to predict HT in AIS patients.
Source link: https://doi.org/10.3389/fneur.2022.897903
The effect of elevated plasma total homocysteine on patients with both ischemic stroke and atrial fibrillation is unclear in patients with stroke caused by other mechanisms. This research was designed to determine the connection between tHcy level and the functional outcome of patients with AF-related strokes. Methods and Results We included consecutive patients with AFu2010-related stroke between 2013 and 2015 from the registry of a realu2010world prospective cohort from 11 major centers in South Korea. We performed a subgroup analysis, based on renal dysfunction's presence since tHcy is greatly affected by renal function. A total of 910 patients with AF-related stroke were evaluated. "In the subgroup report based on renal function, tHcy values above the cutoff point showed a close connection with the unfavorable end only in the normal renal function group. ".
Source link: https://doi.org/10.1161/jaha.121.022138
"Background Prehospitalization is a significant contributor to poor outcomes in both acute and acute myocardial infarction. We wanted to compare the prehospital delay and AMI-related factors between AIS and AMI. Methods and Results We discovered patients with AIS and AMI who were admitted to the 11 Korean Regional Cardiovascular Centers via the emergency room between July 2016 and December 2018. Arrival was described as a prehospital delay of more than three hours, and the generalized linear mixed-u2010effects framework was used to investigate the effects of potential predictors on delayed arrival. Both groups' arrivals were delayed due to the use of emergency medical services. Age and sex had no or minimal influence on delayed arrival in AIS, but, age and female sex were both strongly associated with increased risk of delayed arrival in AMI.
Source link: https://doi.org/10.1161/jaha.121.023214
"Background In patients with ischemic stroke and transient ischemic attack with established guidelines for immediate oral anticoagulants before the index event, there were efforts to establish the diagnostic accuracy of transthoracic and transesophageal echocardiography. Methods and Results This was a retrospective cohort study of consecutive patients with long-term therapeutic direct oral anticoagulants presenting to a single comprehensive stroke center with ischemic stroke or transient ischemic attack, with preceding confirmed evidence for long-term therapeutic drug oral anticoagulants. TEE reported 16 of 102 patients with 20 management-u2010relevant pathologies, excluding TEE and BMTEE. Other pertinent findings were found in a further 3 of 191 patients with TTE and 4 of 101 patients with TEE. Both TTE and TEE patients with established indications for long-term direct oral anticoagulant therapy and stroke who underwent echocardiography discovered a small and similar number of managementu2010risk pathologies and predictive biomarkers that could help guide diagnostic workup in these patients. ".
Source link: https://doi.org/10.1161/jaha.121.024989
"Background Use of inpatient brain magnetic resonance imaging in patients with acute ischemic stroke is highly institution dependent, and it has been correlated with increased length and cost of hospital stay. To justify its funding requirements, we investigated whether inpatient brain MRI in patients with acute ischemic stroke is associated with improved clinical outcomes. Conclusions Inpatient brain MRI in patients with acute ischemic stroke is associated with a significant decrease in mortality and complications in inpatient mortality and infections, despite marginally increasing length and cost of hospitalization.
Source link: https://doi.org/10.1161/jaha.120.016987
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