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Multiple eulipotyphlan mammals, such as shrews, have oral venom delivery systems. Venom helps shrews to hunt and/or hoard preys. A toxin was discovered from venomous submaxillary glands of the shrew Blarinella quadraticauda. BQTX exhibits physical and functional similarity to toxins from snakes, wasps, and snails, displaying an evolutionary relevance of venoms from mammalians and non-mammalians. BQTX causes acute hypertension, blood coagulation, and hypokinesia by potentiating thrombin and factor-XIIa and decreasing plasmin.
Source link: https://doi.org/10.1007/s00018-021-04116-x
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