Advanced searches left 3/3

Human Brain - MedlinePlus Genetics

Summarized by Plex Scholar
Last Updated: 11 January 2023

* If you want to update the article please login/register

Hypomyelination with brainstem and spinal cord involvement and leg spasticity

Hypomyelination with brainstem and spinal cord involvement, as well as leg spasticity, is a condition that affects the brain and spinal cord. HBSL is a special form of leukodystrophy, which is a group of disorders that involve abnormalities of the nervous system's white matter. The white matter consists of nerve fibers coated by a fatty substance called myelin that protects the fibers and aids in the rapid transmission of nerve impulses. The nervous system in HBSL has a reduced tendency to produce myelin. Early motor skills development in HBSL may be normal, but mobility issues generally begin within the first year of an infant's first year. Muscle brute in the legs that worsens over time is a characteristic of HBSL. Most people with HBSL are unable to walk independently. Using magnetic resonance imaging, subtle changes in the brains of people with HBSL can be detected.

Source link: https://medlineplus.gov/genetics/condition/hypomyelination-with-brainstem-and-spinal-cord-involvement-and-leg-spasticity

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions