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High Blood Pressure - U.S. Department of Veterans Affairs

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Last Updated: 11 October 2021

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Blood pressure and albuminuria in a female mouse model of systemic lupus erythematosus: impact of long-term high salt consumption.

Salt consumption is connected to high blood pressure in both human and animal studies. Proof recommends that nutritional salt might be a crucial ecological factor that promotes autoimmune task. Consequently, we assumed that a lasting high-salt diet regimen would speed up the progression of autoimmunity, hypertension, and albuminuria during systemic lupus erythematosus, an autoimmune condition that mostly influences young ladies and has a high occurrence of hypertension and kidney disease. SLE mice were fed a normal or high-salt diet for 24 wk beginning at 10 wk old and ending at 34 wk of age, a time by which women NZBWF1 mice commonly have high blood pressure and exhibition indications of kidney illness. SLE mice fed a high-salt diet regimen had increased flowing autoantibodies, yet the high-salt diet regimen did not significantly impact albuminuria or arterial pressure. These information recommend that a chronic high-salt diet might not speed up renal and cardio consequences commonly linked with SLE.

Source link: https://doi.org/10.1152/ajpregu.00070.2020

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions