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In comparison to reactive macrophages, Peripheral lymph node fine needle aspirations showed a dramatic rise in the number of intermediate and lymphoblastic lymphocytes. In real-time PCR assay and sequencing, Peripheral lymph nodes were found positive for Bartonella henselae DNA. Clinical signs were reduced after treatment with pradofloxacin and doxycycline, as well as negative PCR results. Despite its reported low pathogenicity, B. henselae infection in cats with protracted unexplained fever, lymphadenitis, and IMHA should also be considered in cats with prolonged unexplained fever, fibrosy, and IMHA. In addition, a combination of pradofloxacin and doxycycline could be considered in cats with bartonellosis due to its apparent clinical sensitivity.
Source link: https://onlinelibrary.wiley.com/doi/10.1111/jvim.16415
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