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Heart Failure - Astrophysics Data System

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Last Updated: 19 June 2022

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Detecting congestive heart failure by extracting multimodal features with synthetic minority oversampling technique (SMOTE) for imbalanced data using robust machine learning techniques

"The incidence of congestive heart failure is around 10 per 1000 for Americans over the age of 65 years. The classification between these topics with original information and SMOTE information was carried out using artificial intelligence classifiers such as category and regression tree, support vector machine linear, Na \ u00efve Bayes, semantic network, and set classifiers such as arbitrary woodland, XG boost, averaged semantic network. The outcomes disclose that suggested method with SMOTE enhanced the detection efficiency which can be very effective and computationally reliable tool for automatic discovery of congestive heart failure patients. ".

Source link: https://ui.adsabs.harvard.edu/abs/2022WRCM...32.1079H/abstract


Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate

" A major determinant of maximal workout capacity is the distribution of oxygen to exercising muscular tissues. myo-Inositol trispyrophosphate is a just recently identified membrane-permeant particle that causes allosteric regulation of Hb oxygen binding affinity. In transgenic mice with extreme heart failure caused by cardiac-specific overexpression of G \ u03b1q, i. p. Oral administration of ITPP in drinking water increased Hb p50 and optimum exercise capability in normal and failing mice. Consistent with increased tissue oxygen schedule, ITPP decreased hypoxia inducible factor-1 \ u03b1 mRNA expression in myocardium. It had no result on myocardial contractility in separated mouse cardiac myocytes and did not impact arterial blood pressure in vivo in mice. Thus, ITPP decreases the oxygen binding fondness of Hb, increases tissue oxygen shipment, and increases optimum workout capability in normal mice and mice with severe heart failure. ITPP is thus an appealing candidate for the therapy of patients with decreased exercise ability brought on by heart failure. ".

Source link: https://ui.adsabs.harvard.edu/abs/2009PNAS..106.1926B/abstract


Investigation of measurement area and source-detector distance in diffuse reflectance spectroscopy for leg edema induced by heart failure

" The prevalence of heart failure has increased worldwide. Too much liquid retention frequently causes leg edema in patients with HF, leading to disease development and readmissions. It is essential that the severity of leg edema is routinely examined in patients with HF. Scattered reflectance spectroscopy can discover conditions such as subcutaneous edema. We investigated the perfect location for reviewing leg edema by identifying the subcutaneous frameworks in different regions using ultrasound imaging. Second, optical infiltration deepness was checked out with different source-detector ranges at wavelengths near the absorption height of water. A DRS system enhanced using our searchings for was able to obtain excellent correlation in between water content and absorbance in a leg edema phantom. These findings suggest that leg edema can be examined quantitatively in a DRS system. We expect that this system will help management of fluid retention in patients with HF. ".

Source link: https://ui.adsabs.harvard.edu/abs/2022SPIE11968E..0CN/abstract


A low-cost, paper fluidic platform to detect B-type Natriuretic Peptide (BNP) for Congestive Heart Failure (CHF)

" Today, approximately 5 million Americans are living with Congestive Heart Failure, and this burden is higher for African American communities, even for control groups. Implantable gadgets to measure lung artery pressure are in some cases indicated as a surrogate measure for liquid retention in the lungs created by aggravating heart failure however are often inaccessible to underserved communities due to the expensive expenses of the gadget and surgery. BNP focus are often used to identify CHF into 4 levels of severity on the New York Heart Association scale. By making use of a portable Raman visitor with a 638 nm excitation laser, we retrieve SERRS spectra for the malachite environment-friendly isothiocyanate dye which matches to BNP capture varying from 0. 3 ng/mL to 1 ng/mL. ".

Source link: https://ui.adsabs.harvard.edu/abs/2022SPIE11968E..05C/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions