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The Abstract Background Chlamydia trachomatis and Neisseria gonorrhoeae infections are most common among males in China's menstruation. In MSM community-based organizations, the aim of this pilot study was to determine the possibility of performing rapid nucleic acid testing for chlamydia and gonorrhea. Positive cases were provided with on-site free treatment for chlamydia and gonorrhea. On-site, urine and/or anorectal swab samples were collected and tested for chlamydia and gonorrhea, and the testing findings were published in about 1. 5 h. Only 19. 3% participants had undergone chlamydia and gonorrhea testing, and 69. 9% said they had heard of gonorrhea, although 47. 4% had heard of chlamydia, while 48. 4% had never heard of chlamydia. Conclusions This pilot study showed that the chlamydia and gonorrhea infection rate among MSM is still high, despite the fact that the sampling rate was low.
Source link: https://doi.org/10.1186/s12889-022-13460-x
The Los Angeles County Department of Public Health launched a free home testing service for Chlamydia trachomatis and Neisseria gonorrhoeae, particularly among young African American and Latina women. The service was launched as part of a social media campaign encouraging women to order home collection kits online or by phone.
Source link: https://doi.org/10.2105/ajph.2012.301010
Our analysis investigated whether clinic type influences CT/GC testing and treatment for minors in the Houston, Harris County metropolitan area of Texas, USA; the prevalence of CT/GC infection; treatment rates for minors; and the time, in days, from testing-to-treatment. Before the COVID-19 pandemic, the prevalence of CT and GC at SBCs was remarkably similar to COVID-19 vs.
Source link: https://doi.org/10.3390/biology11040521
ABSTRACT The BD Max CT/GC/TV assay is a genuine multiplex assay for simultaneous detection of chlamydia gonorrhea, and trichomonas. A total of 1,143 women were tested for CT, GC, and television, and then to another 847 for CT and GC, with greef rates for CT, GC, and television of 7. 1%, 2. 3%, and 13. 5%, respectively. According to vaginal swabs, endocervical swabs, female urine samples, and male urine samples, respectively, the sensitivity was 99. 3%, 99. 95 percent, 96%, and 96. 1% for vaginal swabs, endocervical swabs, male urine samples, and male urine samples, respectively. The MAX assay results were in accordance with estimates estimated for the comparator assays. On a benchtop instrument with a wide menu, a CT/GC/TV multiplexed assay can be used to promote local sexually transmitted infection testing at smaller labs and could lead to increased testing for these highly infectious infections.
Source link: https://doi.org/10.1128/jcm.01766-16
In the laboratory diagnosis of gonorrhea, the Gen-Probe PACE system for Neisseria gonorrhoeae was compared to a nonisotopic, chemiluminescent DNA probe test. The rRNA-directed DNA probe hybridizes with the target rRNA, and the hybridized probe is separated from the unhybridized probe by the use of magnetic microparticles. The amount of light produced is directly proportional to the amount of gonococcal target rRNA present in the sample. The DNA probe assay had a sensitivity, specificity, and positive and negative predictive values of 93, 99, 97, and 99%, respectively, in a patient population with a gonococcal disease prevalence of 21%, according to a Statistical review of the overall comparative results. The prototype chemiluminescent DNA test assay, according to the findings of this comparative analysis, is a fast and reliable noncultural alternative for laboratory diagnosis of gonorrhea.
Source link: https://doi.org/10.1128/jcm.27.4.632-635.1989
Limulus amoebocyte lysate assay was used to assess 115 females who were identified as sexual contacts by men with culture-proven gonorrhea. The LAL assay was 100%, with depyrogenated cotton-tipped swabs obtained for the LAL assay and the swabs placed in ten ml of diluent to assay for endotoxin; the negative predictive value of the LAL assay was 100%. Without excluding culture-positive gonorrhea cases, the LAL assay was able to selectively exclude approximately half of the culture-negative gonorrhea contacts, and had avoided these patients from unnecessary therapy and contact tracing, but not inexcluding culture-positive gonorrhea cases.
Source link: https://doi.org/10.1128/jcm.16.3.487-489.1982
In ribosomal fractions, absorption of the sera with nongonococcal organisms did not influence the antibody production, and there was no difference in antigenicity among many N. gonorrhoeae strains. The anti-purified ribosomal fraction antibodies were also used to determine specific antibodies to the purified ribosomal fraction, and this assay revealed that the anti-purified ribosomal fraction antibodies were immunoglobulin G.
Source link: https://doi.org/10.1128/jcm.15.4.668-676.1982
Patients in the total population, 64% of the patients had nonreactive serum and negative cultures; 25% had reactive serum and negative cultures; and 25% had reactive serum and negative cultures. When this latter group was divided by national origins, blacks, and Latin Americans, they were found to have a greater prevalence of reactive serum with a corresponding negative culture than was found in whites. Patients who were initially culture positive and nonreactive in the Gonosticon Test were retested; three out of four patients were retested within 6 to 11 days after the initial screening revealed a positive Gonosticon test.
Source link: https://doi.org/10.1128/am.28.3.431-434.1974
BACKGROUND AND OBJECTIVES Rates of chlamydia and gonorrhea among adolescents are on the rise. We wanted to see if a universal testing service for chlamydia and gonorrhea increased testing rates in urban general pediatric clinic and urban family medicine clinic within a network of federally licensed health care centers, determining the feasibility, cost, and logistic challenges of expanding coverage to 28 primary care clinics within a federally recognized health care centers framework. METHODS In a Denver, Colorado general pediatrics and family medicine clinic, a universal testing quality improvement scheme for male and female patients 14 to 18 years old was introduced. CHOLAMIA and gonorrhea testing in primary care pediatrics and family medicine is a cost-effective method of raising testing results.
Source link: https://doi.org/10.1542/peds.2020-027508
Methods We conducted a retrospective cohort study of all women Veterans in Veterans Health Administration care from January 1, 2018 to December 31, 2019, to examine patient characteristics and health system factors related to gonorrhea and chlamydia testing and case rates among women Veterans in the VHA in 2019. Incidence of gonorrhea and chlamydia among women with a history of military sexual abuse and those with mental illness disorders More than half of chlamydia cases and gonorrhea infections occurred in women living in the South Atlantic census division. According to 100,000 women veterans seen in VHA Gonorrhea, 100,000 woman Veterans seen in the VHA Conclusion Gonorrhea and chlamydia studies are underutilized among women in the VHA, and HIV infection rates are high among younger women.
Source link: https://doi.org/10.1093/ofid/ofab466.1545
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