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GBS - Europe PMC

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Last Updated: 02 August 2022

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Validation and adjustment of modified Erasmus GBS outcome score in Bangladesh.

Patient with Guillain-Barru00e9 syndrome from Bangladesh. Objective We have assessed and improved the results of the updated Erasmus GBS Outcome Score. Patients with GBS from two prospective cohort studies in Bangladesh were included in the Methods Validation cohort. Patients who died within the first week, patients who died within the first week, or patients who were missing GBS disability ratings were ruled out of walking independently. Results A total of 56 patients aged u22656-year-old were registered, with 471 and 366 patients participating in mEGOS validation testing at entry and week 1, respectively. The AUC's forecast of poor results at week 4 were 0. 69 and 0. 8 percent, while week 26 was 0. 67 and 0. 70. Meantless probability of poor results in week 4 was overestimated by mEGOS week 1, except for the likelihood of poor outcomes, which was overestimated by mEGOS week 1. Interpretation The mEGOS results for patients with GBS from Bangladesh show safe outcomes among patients.

Source link: https://europepmc.org/article/MED/35908170


Molecular mapping of drought responsive QTLs during reproductive stage of rice using a GBS (Genotyping by sequencing) based SNP linkage map

The reproductive stage is the most critical stage in rice, where water is required for seed formation. Genotyping by sequencing method developed from Banglami x Ranjit to identify closely linked markers associated with QTLs was created by a high-density SNP based genetic map. Analysis of the genes present in the QTL areas revealed the presence of six candidate genes that were differentially expressed under stress conditions.

Source link: https://europepmc.org/article/PPR/PPR521033


Group B Streptococcus (GBS) colonisation is dynamic over time, whilst GBS capsular polysaccharides-specific antibody remains stable.

Streptococcus, a leading cause of adverse pregnancy outcomes due to invasive infection, is Group B Streptococcus. The aim of this report was to examine longitudinal variations in GBS rectovaginal colonisation, serum, and vaginal GBS capsular polysaccharide-specific antibody levels. By Luminex, and total IgG/A by ELISA, Luminex measured serum and vaginal immunoglobulin A specific to CPS. Out of the 66 participants who attended at least three visits: 14/47 women who were GBS negative at screening became positive in follow-up visits, while 16/19 women who were GBS positive at screening became negative, with 16/19 women who were GBS positive at screening becoming negative. In the serum of people colonized with GBS than in non-colonised, CPS-specific antibodies were higher than those of non-colonized, but not identical in the vaginal and nasal mucosa. We discovered correlations between antibody levels in serum and vaginal and nasal mucosa. The difference between colonisation's dynamics and antibody responses is illuminating, and further investigation is required for vaccine design.

Source link: https://europepmc.org/article/MED/35802786

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions