Follicle Stimulating Hormone - Crossref

Serum Follicle-Stimulating Hormone and 5-Year Change in Adiposity in Healthy Postmenopausal Women

FSH and estradiol's potential independent role in postmenopausal adiposity changes are not well investigated. Methods We examined the relationships between serum FSH and E2 measurements from two x-ray absorptiometry -derived adiposity tests in a sample of 667 women from the Women's Health Initiative Buffalo Osteopertiopertiometry Study, based on cross-sectional and longitudinal studies. An increase in FSH was correlated with a rise in percentages of total body fat, total body fat mass, and subcutaneous adipose tissue, according to updated estimates. Conclusion Although cross-sectional results show that FSH is inversely linked to adiposity, our longitudinal results show that greater rises in FSH were linked to greater rises in total body fat, total body fat mass, and SAT.

Source link: https://doi.org/10.1210/clinem/dgac238

Androgen receptor and miRNA-126* axis controls follicle-stimulating hormone receptor expression in porcine ovarian granulosa cells

Here, we show that AR and miR-126* collaborate to reduce FSHR expression and function in porc follicular granulosa cells. Overexpression of AR decreased in pGCs, while knockdown increased, FSHR mRNA, and protein expression; however, neither manipulation altered FSHR promoter activity. Our results show that the AR/miR-126* axis has synergetic roles in the regulation of FSHR expression and apoptosis in pGCs for the first time.

Source link: https://doi.org/10.1530/rep-15-0517

Protein kinases influence bovine oocyte competence during short-term treatment with recombinant human follicle stimulating hormone

The roles of protein kinase A and protein kinase C were investigated by researchers using activators or inhibitors of these two protein kinases, respectively. When cumulusu2013oocyte complexes were cultured with r-hFSH for the first 6 h, a significant rise in blastocyst formation as a percentage of oocytes in culture in comparison to those matured with r-hFSH for the first 2 or 24 h has been seen. However, PKA inhibitors did not have an effect on the blastocyst yield's stimulatory effects of r-hFSH. Although the developmental capacity of bovine oocytes in vitro can be modulated by both the PKA and PKC pathways, the activation of PKC during short-term treatment can mimic the effect of r-hFSH on bovine oocyte maturation in vitro.

Source link: https://doi.org/10.1530/rep.1.00387

URINARY FOLLICLE STIMULATING HORMONE CHORIONIC GONADOTROPHIN AND OESTROGENS DURING HUMAN PREGNANCY

By double antibody radioimmunoassay, concentrations of follicle stimulating hormone and human chorionic gonadotrophin were determined in randomly voided urine of 50 women during pregnancy. Four pregnant women from the early stages of pregnancy up to delivery were also collected once a week by Daily 24 h urine specimens. In the 24-h specimens, the total oestrogens excretion as well as FSH and HCG excretions were determined. In the serially collected 24 h specimens, the urinary FSH and HCG excretions were found.

Source link: https://doi.org/10.1530/acta.0.0750763

CHANGES IN SERUM LEVELS OF FOLLICLE STIMULATING HORMONE AND LUTEINIZING HORMONE SHORTLY BEFORE AND AFTER PARTURITION IN RATS

ABSTRACT: By radioimmunoassay, a sequence of changes in the serum levels of follicle stimulating hormone and luteinizing hormone from 2 days before to 24 hours after parturition of primiparous Sprague-Dawley rats was traced back to parturition. The average serum LH levels, which had been low for 2 days before and 1 h after parturition, reached a peak at 7 h and reduced to 13 h after parturition. In the pattern of a series of changes in the serum levels near parturition, there were some differences between FSH and LH.

Source link: https://doi.org/10.1530/acta.0.0750491

IMMUNOCHEMICAL ASSAY OF FOLLICLE-STIMULATING AND LUTEINIZING HORMONE IN THE UNCONCENTRATED URINE OF SUB- OR INFERTILE MALES

Log sperm concentration and log FSH excretion may have a significant inverse correlation. No relationship has been found between motility or morphology, log FSH or log LH excretion, though no association has been established. LH excretion was above the normal range in 87 patients with normal testicular size, regardless of sperm counts. However, the mean LH excretion in uni- and bilateral testicular atrophy, and in patients with varicocele was significant in comparison to normal values.

Source link: https://doi.org/10.1530/acta.0.0740631

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