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Fatty Liver Disease - MedlinePlus Genetics

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Last Updated: 13 August 2022

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Non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is a buildup of excess fat in the liver that can lead to liver damage similar to alcohol use, but it does not occur in people who do not drink a lot. The liver is also high in cholesterol, and an individual is expected to have a fatty liver if the liver contains more than 5% to 10% fat. The fat deposits in the liver associated with NAFLD typically cause no symptoms, but they may lead to elevated levels of liver enzymes that are not found in routine blood tests. Between 7 and 30 percent of people with NAFLD suffer inflammation of the liver, which results in liver damage. However, severe or long-term injury can lead to the replacement of normal liver tissue with scar tissue, resulting in irreversible liver disease that causes the liver to stop functioning properly. Scarring in the vein that leads to increased blood pressure in the liver from other digestive organs can lead to elevated blood pressure in the blood vessel, resulting in enlarged blood vessels within the digestive system. Many cases of cirrhosis with no apparent underlying cause have been reported by NAFLD and NASH; at least one-third of people with NASH have cirrhosis. However, a person with NAFLD may not have any of the other conditions that contribute to the metabolic syndrome, and people with any or both of those disorders do not have NAFLD.

Source link: https://medlineplus.gov/genetics/condition/non-alcoholic-fatty-liver-disease


Cryptogenic cirrhosis

People with this disorder have irreversible liver disease caused by liver scarring that occurs mainly in mid- to late adulthood. However, severe or long-term injury may lead to the replacement of normal liver tissue with scar tissue. People with cryptogenic cirrhosis have no signs in the early stages of the disease because the liver has ample normal tissue to function. People with cryptogenic cirrhosis may have elevated blood pressure in the vein that supplies blood to the liver. Cancer of the liver is common in people with cryptogenic cirrhosis.

Source link: https://medlineplus.gov/genetics/condition/cryptogenic-cirrhosis

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions