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Fascia - Europe PMC

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Last Updated: 13 September 2022

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CD201+ fascia progenitors choreograph injury repair

Tight spatiotemporal tuning of tissue inflammation, contraction, and scar-formation can be used to achieve optimal tissue repair and organismal survival1. We show that CD201+ progenitors accelerate wound healing by generating a variety of specialized cell types from proinflammatory fibroblasts to myofibroblasts in a spatiotemporally controlled sequence by using murine skin injury models, single-cell transcriptomics, and genetic lineage tracing and ablation schemes. Both retinoic acid and hypoxia signaling are distinguishing checkpoints that control the transition of fascia progenitor into the proinflammatory and myofibroblast states.

Source link: https://europepmc.org/article/PPR/PPR542428


The Use of Inlay Bridge of the Posterior Fascia as Adjuvants to a Modified Rives-Stoppa Repair for Difficult Abdominal Wall Hernias.

Background Major abdominal wall irregularities are a common complication. Here we detail our method and results of using a bridging mesh when the posterior fascia was unable to be approximated during the repair of large postoperative ventral hernias using the improved Rives-Stoppa technique. Methods An retrospective investigation was conducted to look at all the open abdominal wall hernia surgeries between 2014 and 2020. In comparison to a modified Rives-Stoppa repair using a sublay UltraPro mesh, nineteen patients' mesh inlay bridge was added to a modified Rives-Stoppa repair. Inlay mesh 13 Symbotex composite meshes were woven and 6 Vicryl meshes were used for the inlay mesh. The use of an inlay mesh bridge as an adjuvant to a modified Rives-Stoppa repair with a sublay ultrapro mesh is an efficient method for difficult abdominal wall repairs where the posterior fascia is unable to be determined without tension.

Source link: https://europepmc.org/article/MED/36069008


Endoscopic Plantar Fascia Release Combined With Calcaneal Spur Resection: A Case Series of 40 Patients.

Purpose: This paper investigates the incidences of patients treated with endoscopic plantar fascia release with calcaneal spur resection and explore why the combined procedures cause problems. Methods The medical records of patients treated with endoscopic PFR with CSR from November 2017 to December 2019 were reviewed, as well as a follow-up of more than two years. Conclusion With a high complication rate, the 40 patients treated with endoscopic PFR with CSR for plantar fasciitis had excellent results with a high complication rate; the invasiveness of designing the working space for the combined procedures was deemed to have contributed to the poor outcomes.

Source link: https://europepmc.org/article/MED/36062623


An assessment of plantar fascia with ultrasound findings in patients with plantar fasciitis: a systematic review.

Plantar heel pain in adults is the most common cause of plantar heel pain in adults, with the prevalence estimated at 10% of the general population. Ultrasound imaging is often used to determine the PF thickness, determine the safety of different drugs, and a guide therapeutic strategy in patients with PFS. PFS patients with Preferred Heart The aim of this research was to systematically review the studies that had been previously published to determine the role of ultrasound in the evaluation of PF in patients with PFS. The study focused on the determination of PF in patients with PFS who underwent various treatment including B-mode, shear wave elastography, and color Doppler ultrasound. The studies have compared the PF in patients with PFS under various conditions using different ultrasound techniques. The effectiveness of various treatment of PF in patients with PFS using different ultrasound methods was evaluated in twenty-six studies. The ultrasound was used in 8 of 26 articles as both an assessment instrument of PF and a guide to therapeutic procedures in patients with PFS. In 18 papers, the ultrasound was used as the only assessment device to determine the PF thickness and population changes in patients with PFS. Four articles compared the PF thickness and its intrafascial changes between patients with PFS and healthy controls. Conclusions by using ultrasound to determine the effect of various PF interventions by determining its thickness, echogenicity, and stiffness changes in patients with PFS.

Source link: https://europepmc.org/article/MED/36040577


In Vivo Analysis of the Superficial and Deep Fascia.

Background The wound, fat necrosis, and dead space are all significant risk factors for hypertrophic scarring and surgical site infections. The as-yet poorly researched anatomy of the SF should be identified in order to improve SF suturing. In-vivo, this research is the first to quantify SF throughout the human body. Methods Ultrasound was used to determine SF and deep fascia of ten volunteers at 73 points on 11 body regions, including the upper and lower trunk and limbs. At each point, SF layers, average SF-layer thickness, percent SF thickness, percent SF relative to subcutaneous-tissue thickness, and DF and dermis thickness were measured. Covariate experiments discovered that posterior and anterior chest had higher SF content than gluteus and abdomen. They also showed that the dermis in the posterior and anterior chest progressively increased proportionally to total fascia thickness.

Source link: https://europepmc.org/article/MED/35994352


Structural and Clinical Outcomes After Superior Capsule Reconstruction Using an at least 6-mm thick Fascia Lata Autograft Including the Intermuscular Septum.

However, graft tear rate is highly variable in the previous studies, and the effects of graft tears on clinical outcomes following arthroscopic SCR remain controversial. After arthroscopic SCR using an at least 6-mm thick fascia lata autograft with the intermuscular septum, we investigated the graft tear rate, timing of graft tear, and the effects of graft tears on clinical outcomes. Methods This retrospective multi-institutional review included 154 patients with irreparable rotator cuff tears who underwent arthroscopic SCR with an at least 6-mm thick fascia lata autograft, with the intermuscular septum and a minimum 2-year follow-up. Patients with and without graft tears, 1 baseline, 2 visual analog scale, 3 Japanese Orthopedic Association JOA score, 4 American Shoulder and Elbow Surgeons ASES shoulder score, and 5 active range of motion were compared. Conclusions The overall graft tear rate in 154 patients was 18. 7%. All P 0. 0001. 12 after SCR in both patients with and without graft tears improved dramatically. ASAES, JOA, and JOA scores increased significantly after SCR in both patients with and without graft tears increased significantly. However, patients with graft tears showed significantly lower postoperative VAS, ASES, and JOA ratings of 1. 9, 75. 2, and 77. 4, respectively, than those without graft tears 0. 5, 93. 1, and 92. 3, respectively; all P 0. 01. Conclusions The overall graft tear rate after arthroscopic SCR using a minimum 6-mm thick fascia lata autograft with the intermuscular septum was low 11. 7%, much lower than those reported in previous studies. After SCR, Graft regeneration was associated with improved clinical outcomes.

Source link: https://europepmc.org/article/MED/35998778


Duraplasty with autologous nuchal ligament fascia to reduce postoperative complications in pediatric patients undergoing neoplasia resection with a suboccipital midline approach.

Purpose Through a suboccipital midline approach, the authors sought to investigate the safety and effectiveness of an autologous nuchal ligament for dural repair in pediatric patients undergoing tumor resection. Methods Pediatric patients with posterior fossa neoplasia who underwent surgery using a suboccipital midline strategy were retrospectively reviewed by pediatric physicians. Depending on whether artificial duraplasty material or autologous nuchal ligament was used to repair the dura, the patients were divided into artificial graft and autograft groups. Compared to the artificial graft group, the autograft group had significantly fewer postoperative problems, especially pseudomeningocele. The autologous fascia of the nuchal ligament of the nuchal ligament reduced pseudomeningocele more than CSF leakage and meningitis, in particular. However, both ependymoma and postoperative hydrocephalus exacerbation were more likely to cause meningitis than with pseudomeningocele and CSF leak.

Source link: https://europepmc.org/article/MED/35986733


Superior Capsule Reconstruction with Fascia Lata Allograft has Initial Stiffness and Ultimate Load Comparable to the Native Shoulder Superior Capsule: A Cadaveric Biomechanical Study.

Purpose of the study The aim of this research was to compare the biomechanical characteristics of a Fascia Lata Superior Capsule Reconstruction to the native superior capsule. Methods The native superior capsule of eight cadaveric shoulders was tested for 30 cycles from 10N to 50N in 20 degrees of glenohumeral abduction, followed by load to failure at 60 mm/min. FL-SCR was performed as described for the native capsule following native superior capsule testing. The initial stiffness for the FL-SCR and the native superior capsule were not significantly different during load to failure. The native superior capsule's linear stiffness and yield load were much higher than that of the FL-SCR. Clinical relevance The flaws of FL allograft make it an appealing option for superior capsule reconstruction as a graft alternative.

Source link: https://europepmc.org/article/MED/35988793


Clinical and cost-effectiveness of paramedic administered fascia iliaca compartment block for emergency hip fracture (RAPID 2)-protocol for an individually randomised parallel-group trial.

In this subsequent research, we will investigate the safety, clinical, and cost-effectiveness of paramedic-provided FICB as pain relief to patients with suspected hip fracture in the prehospital setting. FICB will be administered by hospital consultants in five locations in England and Wales. From pre-randomisation to arrival at the emergency department, the primary result is a change in pain scores. Patients will be tracked using NHS digital and the SAIL databank to track patient outcomes using anonymised linked data in an effective research methodology and questionnaires to collect patient-reported outcomes at 1 and 4 months. Discussion The trial will help determine whether or not medicated FICB is a safe, clinically, and cost-effective treatment for suspected hip fracture in the pre-hospital setting. If and when clinical guidelines either advocate or oppose the use of FICB in routine use in this setting, an effect will be shown.

Source link: https://europepmc.org/article/MED/35978361

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions