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Family History - Springer Nature

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Last Updated: 06 August 2022

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Early-onset diabetes involving three consecutive generations had different clinical features from age-matched type 2 diabetes without a family history in China

Purpose is a form of diabetes that is often misdiagnosed as type 1 diabetes or type 2 diabetes. The aim of our research was to investigate the clinical characteristics of early-onset diabetes in a Chinese diabetes cohort involving three generations. Methods Of 6470 type 2 diabetic patients, 105 of whom were named as eDia3, were categorized as eDia3 in the United States. We compared the clinical characteristics of 89 eDia3 patients without a family history of diabetes in the aftermath of a case-u2013control match on age. Conclusions The eDia3 patients had specific medical signs.

Source link: https://doi.org/10.1007/s12020-022-03144-2


Reduced gluteofemoral (subcutaneous) fat mass in young Japanese women with family history of type 2 diabetes: an exploratory analysis

Subcutaneous adipose tissue growth limitations may be characteristic of first-degree relatives of type 2 diabetes. We tested the possibility that family history of type 2 diabetes may be correlated with reduced peripheral fat mass. For FHD+ as a dependent variable in a total population, there were multivariate logistic regression studies for FHD+ as a dependent variable. BMI stood at 21 kg/m2 but not between FHD+ and FHD-nonathletics, which did not differ between FHD+ and FHD-nonathletics. Despite similar BMI, body fat percentage, and serum leptin in FHD+ nonathletes, they were lower in FHD+ nonathletes. Despite lower BMI in a total population, FHD+ women had lower HDL cholesterol amid lower BMI. Independent relationships of FHD+ with BMI and HDL cholesterol were shown by multivariate logistic regression studies. FHD may be related to reduced subcutaneous fat mass in young Japanese women, which suggests reduced adipose tissue expansionability.

Source link: https://doi.org/10.1038/s41598-022-16890-0


Combined associations of family history and self-management with age at diagnosis and cardiometabolic risk in 86,931 patients with type 2 diabetes: Joint Asia Diabetes Evaluation (JADE) Register from 11 countries

Background The past of type 2 diabetes can reveal shared genotypes, environments, and/or behaviors. Methods of Assessment In a cross-sectional review of the prospective Joint Asia Diabetes Evaluation Register, which featured patients from 427 clinics in 11 Asian countries/regions in 2007-2021, we characterized positive FamH as diseased parents/siblings, and self-monitoring of blood glucose as healthy lifestyles and regular self-monitoring of blood glucose as affecting blood glucose levels. The incidence of FamH varied from 39. 1% to 85. 3% in various regions, with FamH affecting mother being the most common. [50. 1 ] The FamH+u22652 healthy lifestyle group had the same age at diagnosis [48. 2 ] as the non-FamH+2 healthy lifestyle group [50. 1 ]. The FamH group with affected parents had higher risks of hyperglycemia, hypertension, and dyslipidemia than the FamH group with contaminated siblings, with the lowest odds in the non-FamH group.

Source link: https://doi.org/10.1186/s12916-022-02424-y

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions