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Esophageal Cancer - Wiley Online Library

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Last Updated: 13 May 2022

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Meat consumption and risk of esophageal and gastric cancer in the Golestan Cohort Study, Iran

Some gastrointestinal cancers are associated with red meat and processed meat. In a high-risk population, this study aims to determine the connection between various meat types and esophageal and gastric cancer. The Golestan Cohort Study is a population-based survey of 50,045 people aged 40 to 75 from northeast Iran. For the relationship between meat types and cancer, we used proportional hazards regression models to determine hazard ratios and their respective 95% confidence intervals. GC's risk of GC was elevated for people consuming both total red meat and red meat separately. 1. 23 GC (red meat and non-cardia GC) The HR for red meat and non-cardia GC was 1. 23. In conclusion, red meat intake in this high-risk population is linked to GC but not EC, indicating a significant role for this modifiable factor in determining the burden of GC.

Source link: https://onlinelibrary.wiley.com/doi/10.1002/ijc.34056


Novel cancer‐specific epidermal growth factor receptor antibody obtained from the serum of esophageal cancer patients with long‐term survival

Abstract Although esophageal cancer has a poor prognosis after recurrence, some patients have survived long-term even after recurrence. We hypothesized that induction of either antitumor Abs or antitumor-specific CTLs may have a long-term effect in patients with recurrence or distant metastases. We aimed to find Abs that specifically bind to cancer cells by using serum samples from patients with a positive prognosis. KT112 is primarily bound to EGFR-positive cancer cells, but it is unable to bind to normal esophageal cells, although not able to bind to normal esophageal cells. Moreover, KT112 was characterized by EGFR expressions on cancer cells but not on the recombinant extracellular domain of EGFR. The Abdomescence squamous cell carcinoma tissue contained 17. 4% of esophageal squamous cell carcinoma tissue but not with any other cancer or normal tissue, indicating that the Ab recognizes cancer-specific EGFR and may have contributed to tumor suppression in patients with esophageal cancer patients.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/cas.15350

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions