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Background: Bleeding from the upper gastrointestinal tract is a medical emergency. Following acute upper gastrointestinal bleeding, urgent endoscopy is a common problem for endoscopists. However, the presence of blood, blood products, and other residues in the stomach is a significant issue for endoscopists during acute endoscopy. In these patients, intravenous erythromycin before endoscopy increases the visualization of the gastric and duodenal mucosa. Aim: Since oral erythromycin is more affordable and more convenient to use, we'll investigate the effect of oral erythromycin on endoscopy in patients with elevated gastrointestinal bleeding. Methods: This interventional study was carried out in Lahore General Hospital's Medicine department for the period of six months from January 2021 to June 2021. Patients with acute upper GI bleeding within 12 hours were considered sequentially. Patients were either randomly assigned to an oral erythromycin suspension or a placebo three hours before endoscopy, or placebo placebo. In the erythromycin group, the quality of endoscopy was much higher than placebo compared to placebo. Erythromycin did not reduce endoscopic time and hospital stay, not reduce hospital stay. There was no statistically significant association between erythromycin therapy and bleeding diagnosis, the need for a new endoscopy, the number of blood transfusions, and the number of endoscopic procedures There was no statistically significant relationship between the use of erythromycin and bleeding prevention, no statistically significant association was found between the use of erythromycin and the diagnosis of bleeding, the introduction of bleeding, the need for a new endoscopy, the number of blood transfusions, Conclusion: In our study, oral suspension of erythromycin before endoscopy in patients with acute upper gastrointestinal bleeding resulted in high endoscopy quality. There was also no significant difference between revision endoscopies and blood transfusions.
Source link: https://zenodo.org/record/5764828
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