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Unwanted changes in blood pressure, lipid metabolism, and erythrocytosis have been attributed to Androgen abuse. Compared to baseline, systolic and diastolic blood pressure increased 6. 87 and 3. 17 mmHg during androgen use. LDL cholesterol and ApoB increased 0. 45 mmol/dl and 18. 2 mg/dl respectively, while HDL cholesterol, ApoA, and Lp decreased by 0. 40 mmol/L, 36. 6 mg/dl, 37. 6%, respectively. In conclusion, androgen use in conjunction with small but clinically relevant adverse changes in blood pressure, lipid metabolism, and erythrocytosis, which are quickly reversible after cessation. The effect of androgen therapy on cardiovascular disease remains unclear as the follow-up was limited to one year.
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