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According to existing studies on toxicity and epidemiology, the most common route of exposure is inhalation of dust inhaled by professionally affected cohorts. Bentonite itself is no more harmful than any other unregulated substance and has not been designated as carcinogenic by any authority or advisory body, but in certain bentonites, a patchy layer of breathable crystalline silica is suspected for humans may be carcinogenic.
Source link: https://zenodo.org/record/6563397
Molecular epidemiology studies in Leprosy are particularly challenging, mainly because of the disease's inherent characteristics as well as its yet uncultivated causative agents, Mycobacterium leprae and M. leprosis. Despite significant advances in understanding leprosy bacilli's genetics using genomic techniques, the precise mechanisms of transmission are still unclear, and the causes underlying disease pathological variability in various patients remain as significant gaps in our knowledge of leprosy. This has provided the foundation for molecular epidemiology research that is leading to a better understanding of strain evolution associated with ancient human migrations, as well as phylogeographical evidence of disease spread around the world. We conclude, highlighting the current research and challenges that remain in the field of leprosy's molecular epidemiology.
Source link: https://zenodo.org/record/6544516
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