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Enthesitis - PubMed

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Last Updated: 24 January 2023

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Recent updates in enthesitis-related arthritis.

Enthesitis-related arthritis, which falls under the umbrella of disorders present in juvenile spondyloarthropathy, is a group of juvenile idiopathic arthritis. HLA B27's effect on gut dysbiosis is one of many hypotheses relating HLA B27 to era, one of them being linked to ERA. However, recent reports indicate that gut dysbiosis is most likely not influenced by HLA B27. axial disease is present in 50-60 percent on MRI, although children have arthritis and enthesitis. Children can be characterized as disease patients and chronic disease using a data-driven strategy. An abridged version of juvenile spondyloarthropathy disease severity may be able to increase the incidence of chronic phase reactions and Schober's test, which were also good as the original score, may increase the possibility of routine use. Secukinumab has a higher response rate in children with ERA than ever before, and could be a good alternative to anti-TNF therapy. Initial results with tofacitinib also look promising.

Source link: https://doi.org/10.1007/s00296-023-05274-w


Longitudinal Follow-Up Using the Heel Enthesitis Magnetic Resonance Imaging Scoring System (HEMRIS) Shows Minimal Changes in Heel Enthesitis Assessed in Spondyloarthritis and Psoriasis Patients.

The Heel Enthesitis Magnetic Resonance Imaging Scoring System was developed for reliable diagnosis of enthesitis. Regardless of the presence of clinical heel enthritisitis, this single-center observational research followed patients with SpA and psoriasis for two years. Using Spearman's correlation coefficient, the association between changes in the HEMRIS and changes in clinical parameters was investigated. Our findings show that MRI-findings of enthesitis treated with HEMRIS changed in a small number of patients in a one-year period in an observational setting. HEMRIS was not connected to changes in clinical disease prevalence, although studies in HEMRIS were not correlated with changes in clinical disease activity.

Source link: https://doi.org/10.3390/jpm12111765


Bibliometric analysis of publications on enthesitis in spondyloarthritis in 2012-2021 based on web of science core collection databases.

From a bibliometric perspective, this research sought to provide a broad view of enthesitis-related studies and examine the direction of hot topics and future research trends. In the Web of Science Core Collection databases, the global literature on enthesitis published from 2012 to 2021 were searched. As of June 29, 2022, the United States was the top country with the highest publication counts, highest h-index, and the largest collaboration network among these countries. Professor Mease PJ and Journal of Rheumatology were the most influential journal and best author, respectively, according to Journal of Rheumatology and Professor Mease PJ. In the previous ten years, more and more attention has been paid to enthesitis. Antigenetic and antibody production against these conditions are among the topics discussed in the present study.

Source link: https://doi.org/10.1007/s00296-022-05227-9


The identification of association between ultrasonographic enthesitis and the ASAS Health Index in patients with axial spondyloarthritis.

In patients with axial spondyloarthritis, this study was conducted to determine correlation between the entheseal abnormalities in ultrasound and the Assessment of Spondyloarthritis International Society Health Index. The MASEI total score and the MASEI sub-scores were calculated. To determine patients' health and disease use, the ASAS HI and other SpA tools were used. The MASEI total score was 8. 4 u00b1 6. 8, while MASEI's activity was 8. 8 percent, with the mean MASEI-structural injury being 3. 8 %u00b1 4. 5. There was no association between ASAS HI and MASEI total scores. According to this report, active entheseal lesions rather than structural lesions affected the ASAS HI score. With ultrasonography, we recommend enthnemy evaluation as part of other methods for monitoring patient health with axSpA.

Source link: https://doi.org/10.1007/s00296-022-05188-z

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions