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Dysphagia - ClinicalTrials.gov

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Last Updated: 13 September 2022

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Slow-Stream Expiratory Muscle Strength Training for Veterans With Dysphagia Living in Long-term Care

This review will be conducted in Sunnybrook Veterans Centre, a long-term care facility for many people over the age of 85 years with dysphagia. These people with dysphagia are particularly vulnerable to respiratory tract infections due to increased demand for feeding and oral care, reduced mobility, multiple medical comorbidities, polypharmacy, and rising frailty. During swallowing in community-dwelling adults over the age of 65 years, expiratory muscle strength training delivered within a four-week intensive course has showed promising success in improving cough control and reducing laryngeal penetration/aspiration during swallowing. The EMST150 is a handheld device with adjustable resistance that prepares respiratory muscles used in exhalation. The Residents' Council executive and meeting attendees expressed dissatisfaction, and the final protocol was accepted in a Residents' Council meeting. The aim of this research is to determine whether a new, slower-stream EMST protocol of 12 sets/week over eight weeks is an effective therapy for improving lung clearance and swallowing safety in LTC residents over the age of 85 years with dysphagia. The International Dysphagia Diet Standardization Initiative's Functional Diet Scale's pre and post intervention, as well as a 3 month follow-up, will determine the secondary end of swallowing-related quality of life. In the three months post-intervention, incidence of respiratory tract infections that neces antibiotics will be determined and compared to wider institutional findings.

Source link: https://clinicaltrials.gov/ct2/show/NCT04064333


Defining Novel Pharyngeal Pressure Metrics to Predict Dysphagia Treatment Outcomes and Clinical Prognosis Using High-resolution Manometry

This multi-center trial will track a cohort of Veterans with dysphagia for eight weeks as they begin medically guided oropharyngeal exercises with oropharyngeal enhancement as the primary goal. At three time points: baseline, 4-6 weeks post-treatment, and 8 weeks post-treatment will be evaluated. Without completion of a therapy process, a non-dysphagic Veteran control group will also collect data at various time points. This report will establish a consistent outcome measurement framework for dysphagia clinical care and research, assuring clinical stability and paving the way for a personalized medicine approach for dysphagia rehabilitation in veterans.

Source link: https://clinicaltrials.gov/ct2/show/NCT04569097


How Does Variation in Assessment and Clinical Management of Dysphagia in Acute Stroke Affect Development of Stroke-associated Pneumonia (SAP)?

Stroke-Associated Pneumonia is a disease that causes the risk of stroke patients in the first 72 hours of admission. How does dysphagia testing and clinical care during the first 72 hours of admission influence stroke patients? Patients with acute stroke in England and Wales are recommended to be screened using a trusted multi-item screening device within four hours of admission, as well as a comprehensive speech and language therapy assessment within 72 hours of admission. The Sentinel Stroke National Audit Programme is England and Wales' national register of strokes and gathers statistics for stroke patients in the majority of acute hospitals. A delay in screening and specialty SLT assessment increased the risk of stroke-related pneumonia, and a decrease in mortality after stroke could also reduce mortality after stroke. Methods: The Yorkshire and the Humber Sheffield Research Ethics Committee and the Sheffield Hallam University Research Ethics Committee will both be seeking ethical approval from the Yorkshire and the Humber Sheffield Research Ethics Committee and the Research Ethics Committee. Accessing anonymised patient level data from SSNAP requires contacting the Healthcare Quality Improvement Programme, who sponsor SSNAP and are the data controller. Systematic research and analysis of the literature will be conducted on a systematic basis: A systematic search and analysis of the literature will be conducted on the subject of acute stroke and the risk of developing stroke aspiration pneumonia will be conducted in the Center for Investigative Research and Dissemination guidelines on systematic reviews. Patient information will be obtained from the medical notes of 30 consecutive patients admitted to the Hyper Acute Stroke Unit in Sheffield Teaching Hospitals NHS Foundation Trust's Hyper Acute Stroke Unit. Five interviews with stroke patients and caregivers of patients who have received the dysphagia screen and/or underwent a comprehensive SLT swallow study will be included in the article. The electronic questionnaire will be piloted across a target group of SLTs from the Trent Dysphagia Clinical Excellence Network who will access the pilot questionnaire and provide feedback via their virtual Basecamp network. Following their feedback, the questionnaire will be expanded and published nationally to the SLT Clinical Lead for Stroke Unit in hospitals in England and Wales, who are registered on the Sentinel Stroke National Audit Programme Register, which is part of the Sentinel Stroke National Audit Programme. From the researcher and analysis team's existing professional networks, larger research networks, for example, the Council for Allied Health Professions Research, social media pages like Twitter, and information that is publicly available, the SLT Clinical Lead for Stroke will be identified. In cases where there is no pre-existing professional relationship or the information about the subject matter is not publicly available, the researcher will contact a third party, with the request that they circulate information about the study with the researcher's contact information, with the suggestion that the most appropriate individual contact the researcher to request more information if they are interested in finding more details.

Source link: https://clinicaltrials.gov/ct2/show/NCT04779710


Safety and Efficacy of the Swallow Expansion Device (SED) for Improvement of Swallowing in Patients With Life-threatening Aspiration Secondary to Feeding Tube Dependent Oropharyngeal Dysphagia: A Single-site, Open-label, Phase 1 Human Trial

Many people with severe swallowing difficulties are unable to open their upper esophageal sphincter, a circular band of muscle that looks like a valve, allowing food to penetrate the esophagus and descend into the stomach. People with extreme dysphagia may cough and choke on food, liquid, even their own saliva. People who were missing feeding tubes for 100% of their diet as a result of severe swallowing difficulties had a long suture thread attached to their throat. Patients were able to reveal their upper esophageal sphincter after pulling the two ends of the suture thread forward. In fact, their swallowing improved so much that three patients went home with the suture in place so they could eat by mouth. The current SED model looks like the letter "T" or a business tack used to stick paper on a wall or board, as shown by the letter "T. " The SED post is similar to the bottom part of the "T" or pointy portion of the tack, but instead of ending with a word, the end has a small ring. After the neck skin heals over the plate, the neck skin reveals permanently sticks out from the throat, similar to a skin piercing. When the SED post is pulled forward with their fingers on the ring, a person can eat with the SED by allowing food to enter their esophagus. Both sheep and human cadaver studies have found that the SED is able to significantly open the upper esophageal sphincter.

Source link: https://clinicaltrials.gov/ct2/show/NCT02296528

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions