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Dyspepsia - DOAJ

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Last Updated: 25 July 2022

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Factors associated with mood disorders and the efficacy of the targeted treatment of functional dyspepsia: A randomized clinical trial

Patients with FD with MDs and acid reflux were treated with flupentixol and melitracen, as well as acid-suppressive therapy, but those without acid reflux did not receive AST. Patients with FD without MDs were randomly administered H2RAs or PPIs. The primary endpoints of this analysis were factors related to MDs and changes in gastro symptoms and MDs in patients with FD. 0. 05> [GI: 72. 22% vs. 41. 22% and 72. 22%, respectively vs. 38. 9% vs. 38. 4%] at week 2, all P 0. 05]. Furthermore, the remission rate of overall GI symptoms in group E was significantly higher in group E than that in group D [60. 29% vs. 42. 65%, P 0. 05].

Source link: https://doi.org/10.3389/fmed.2022.859661


Smaller CO2 injection volume and lower gastric pressure induce bothersome symptoms in drug-resistant functional dyspepsia patients with less frequent belching.

Following the CO2 injection, patients experienced abdominal pain and troubling signs at baseline, with gastric pressure at baseline and gastric pressure at baseline, as well as the CO2 injection volume. In drug-resistant FD patients with initial and bothersome signs in the upper abdomen, they had significantly lower gastric pressure and significantly less CO2 injection volume than in non-FD patients. Bothersome signs in drug-resistant FD patients contribute to lower gastric pressure and less CO2 injection volume than those who are not.

Source link: https://doi.org/10.1371/journal.pone.0271456


Chinese Herbal Medicine for Functional Dyspepsia With Psychological Disorders: A Systematic Review and Meta-Analysis

Chinese herbal medicine has a potent concurrent role in the treatment of FD, particularly for patients with concurrent psychological disorders. The actual risk of CHM in the treatment of FD was higher than that in the placebo group, according to the study [relative risk = 1. 76; 95% confidence interval 0. 1]. CHM was only treated in the study group, and the control group was treated with prokinetic agents mixed with flupentixol melitracen. CHM in the treatment of FD's total effective rate of CHM was higher than that of the control group [RR = 1. 17; 95% CI P 0. 0001]. Conclusions :The experimental group and the control group had no significant adverse effects on FD and enhancing the psychological disorders of anxiety and depression in patients with FD, according to the latest reports; Z = 0. 14; 95% CI ; P = 0. 19; P = 0. 19; P = 0. 44; P = 0. 19); CONCL; P = 0. 79; P = 0. 20; P = 0. 19)[MD = 0. 14; 95% CI ; P = 0. 79]; Z = 0. 14; Z = 0. 14; Z = 0. 14; Z = 0. 14; P = 0. 74; Z = 0. 14; Z = 0. 24; P = 0. 14; P = 0. 34; Z = 1. 24; [Z = 0. 54; P = 0. 19; Z = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 19; P = 0. 74; P = 0. 19; P = 0. 19; P = 0. 20; P = 0. 74;.

Source link: https://doi.org/10.3389/fnins.2022.933290


Effect of Kvass on Improving Functional Dyspepsia in Rats

Patients with gastrointestinal diseases often have a poor response to conventional drug therapy and suffer from adverse reactions, particularly patients with gastrointestinal disease. To improve the symptoms of FD patients, Kvass can be used as a medical drink with side effects. In the high-dose group, the contents of ghrelin, motilin, and gatrin were both elevated, and the reduction of the treatment group's vaping peptide was also reduced, compared to those of the model group; the number of pepsin was also elevated relative to that of the placebo group; a high dose of ghrelin, motilin, and gastrin in the plasma was significantly reduced, and reduced the amount of vaso.

Source link: https://doi.org/10.1155/2022/5169892


Saam Acupuncture for Treating Functional Dyspepsia: A Feasibility Randomized Controlled Trial

In Korean medicine clinical settings, Saam acupuncture, a variation of traditional Korean acupuncture, is frequently used to treat FD. Patients with FD were randomly assigned to either an acupuncture plus usual care group or a common care group, according to the ROME III criteria. In the acupuncture group three times a week for four weeks, personalized FD and systemic signs was administered, based on individual FD and systemic complaints. At Week 4 and the following comparisons revealed significant differences between the two groups in the dyspepsia symptoms measured by GIS, VAS, and PGA, with no significant difference between the two groups in the dyspepsia symptoms as measured by GIS, VAS, and PGA. In particular, the early satiety subscore of GIS in the Saam acupuncture group was significantly enhanced in comparison to the usual care group at Week 4. acupuncture in Saam can be a simple, preliminarily safe, and safe form of FD treatment.

Source link: https://doi.org/10.1155/2022/2581041


Association between Dietary Macronutrient Intake and Symptoms in Uninvestigated Dyspepsia: Evidence from a Population-Based, Cross-Sectional Study

We looked at the connection between diet macronutrients and dyspeptic signs in patients with dyspepsia and reduced symptoms in patients with dyspepsia through a population-based survey, seeking to establish macronutrient intake thresholds to predict or prevent dyspepsia and reduce dyspepsia. Methods: In this population-based, cross-sectional study, a total of 4763 Iranian people were included. The evaluation was then repeated in those with UD to determine intake thresholds for lowering UD symptoms. Compared to people without UD, those with UD had a lower intake of carbohydrates and a higher intake of fats, while protein and energy intakes did not differ, with UD having a lower intake of carbohydrates and a higher intake of fats. According to the above, increased dietary fat and protein intakes were associated with a greater incidence of postprandial fullness and epigastric pain. Prospective studies that rigorously manipulate diet macronutrient composition are required to investigate the benefits of dietary changes to reduce symptoms in people with UD.

Source link: https://doi.org/10.3390/nu14132577


Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

Background and Abstract Background Functional dyspepsia is one of the most common functional gastrointestinal disorders. Our research hopes to continue researching the clinical validity and safety of Zhizhu Capsule in the treatment of patients with FD-PDS patients as a result of a preliminary clinical trial. The primary study will determine whether the response rate for FD-PDS VAS scores in the two groups before and after 8 weeks of treatment with an alpha level of 0. 05. This trial will commence with an 8-week double-blind trial period to look at the effects of long-term mediation in comparison to the placebo group, as opposed to the previous clinical trial that focussed on FD-PDS.

Source link: https://doi.org/10.1186/s13063-022-06396-5


Efficacy of Chenodeoxycholic Acid and Ursodeoxycholic Acid Treatments for Refractory Functional Dyspepsia

Despite at least two medical treatments, patients with refractory dysfunction dyspepsia are diagnosed when signs persist for at least six months. A narrowed cystic duct, Sphincter of Oddi dysfunction, microlithiasis, and gallbladder dyskinesia are all suspected as possible causes of functional biliary dyspepsia. We investigated the therapeutic properties of litholytic agents. RFD patients were prospectively enrolling in six tertiary medical centers. For 12 weeks, all subjects were exposed to chenodeoxycholic and ursodeoxycholic acids twice daily. Before and after treatment, the 7-point global symptom scale test scores were determined. Before therapy, the mean number and duration of symptoms were 2. 4 and 48. 2 months, with a median of 3. 3 FD-related drugs taking place. The mean global symptom severity scale score changed from 5. 6 pretreatment to 2. 6 posttreatment. Conclusions: CNU improved the signs of RFD patients who did not respond to conventional medications, which did not respond to conventional drugs. Patients with RFD and biliary dyspepsia as a result of biliary microlithiasis are often prescribed by Litholytic agents, and biliary dyspepsia are among the treatment options available to patients with RFD and biliary dyspepsia secondary to biliary microlithiasis are common treatment approaches.

Source link: https://doi.org/10.3390/jcm11113190


Overlap of Gastroesophageal Reflux Disease and Functional Dyspepsia and Yield of Esophagogastroduodenoscopy in Patients Clinically Fulfilling the Rome IV Criteria for Functional Dyspepsia

Patients with typical reflux disease and functional dyspepsia, as well as the production of esophagogastroduoscopy in patients clinically presenting with FD were recruited and underwent esophagogodescopy. AimTo investigate the relationship between gastroesophageal reflux disease and functional dyspepsia, as well as the development of esophagogastroduoscopy in patients clinically presenting with FD. u22652 GERD was divided into non-erosive reflux disease and erosive reflux disease, and erosive reflux disease, and erosive reflux disease and erosive reflux disease, and FD was divided into epigastric pain syndrome and postprandial distress syndrome. Endoscopic findings that may have influenced patient-u2019 symptoms were deemed medically relevant by the endoscopic findings. In GERD-FD cross-over FD overlap than in FD-only, postprandial distress syndrome was more prevalent in GERD-FD overlap than in FD-only. Conclusion: The prevalence of gastroduodenal ulcers in patients who were medically diagnosed with the FD with and without reflux symptoms was 0. 6 percent and 4. 7 percent, respectively.

Source link: https://doi.org/10.3389/fmed.2022.910929


Comparison of patient tolerance and acceptability of magnet-controlled capsule endoscopy and flexible endoscopy in the investigation of dyspepsia

EGD and transnasal endoscopy's acceptance and acceptance in this research have been compared to magnet-controlled capsule endoscopy. Patients and methods In the investigation of dyspepsia, a comparison of MACE with EGD and TNE was made. Using the Endoscopy Concerns Scale and Universal Patient Centeredness Questionnaire, researchers were investigating factors that influence patient tolerance and acceptanceability. Patients were more accepting of MACE than TNE, with a UPC-Q score lower for EGD and TNE than MACE, and a post-procedure ECS score higher for EGD and TNE than MACE, and a post-procedure ECS higher than MACE. Even if EGD or TNE respectively was later advised to obtain biopsies in half of examinations, MACE would be preferred by 83 percent and 67% of patients. Conclusions Gagging and choking during instrumentation, the primary causes of patient distress during EGD, occurred less during TNE, but tolerance, acceptance, and patient experience favored MACE over TNE.

Source link: https://doi.org/10.1055/a-1790-5996

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions