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Disseminated Intravascular Coagulation - Astrophysics Data System

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Last Updated: 13 November 2021

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Retrospective review of 27 European cases of fatal elephant endotheliotropic herpesvirus-haemorrhagic disease reveals evidence of disseminated intravascular coagulation

Elephant endotheliotropic herpesvirus haemorrhagic disease is extensively recognized as one of the most typical reason of death in young Asian elephants in bondage. The goal of the present study was to execute a blinded, retrospective pathology testimonial of European EEHV-HD deaths, comprising the largest organized analysis of EEHV-HD pathology to day. Microthrombi were observed in 63% of situations in a number of body organs, including lungs, which, along with prevalent haemorrhage and thrombocytopenia reported in EEHV-HD case records, supports the visibility of overt DIC as a significant haemostatic issue of active EEHV infection. Systemic inflammation observed in the absence of microbial infection might be triggered by cytokine launch syndrome. Findings strengthen the need to check out cytokine responses and haemostatic standing during asymptomatic and symptomatic EEHV viraemia, to possibly support using anti-inflammatory treatment combined with anti-viral therapy and cardio support.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..1114173P/abstract


Disseminated intravascular coagulation associated organ failure in obstetric patients admitted to intensive care units: a multicenter study in China

The durations of health center remain and ICU remain were recorded as secondary end results. Among 297 ICU admissions for obstetric illness, there were 87 DIC cases, with an approximated DIC incidence of 87 per 87,580 shipments. Compared with patients without DIC, those with DIC had greater rates of numerous body organ dysfunction syndrome/death, body organ failing, amongst which body organ failure consisted of intense kidney failing, respiratory failure, disruption of consciousness and DIC team additionally had greater rates of enormous transfusion, hysterectomy, longer ICU and health center keeps. DIC and amniotic liquid embolism were independent risk elements for body organ failure in patients admitted to the ICU. Postpartum hemorrhage was the leading reason for DIC connected body organ failing in obstetrics admitted to the ICU. The control of obstetric blood loss in a prompt manner may improve obstetric diagnoses.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..1116379Z/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions