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Diabetic Foot - DOAJ

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Last Updated: 28 August 2022

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The engagement of orthopaedic surgeons in diabetic foot care in England

Foot care in AimsDiabetic foot care is a significant strain on the NHS in England. The 2018 National Diabetic Foot Audit revealed that we had a national survey to determine the current participation of orthopaedic surgeons in diabetic foot care in England. MethodsA questionnaire was sent to all 136 NHS trusts audited in the 2018 National Diabetic Foot Audit. ResultsOverall, 123 trusts responded, of which 117 admitted diabetic foot disease patients and 113 had an orthopaedic foot and ankle surgeon, and 113 had an orthopaedic foot and ankle surgeon. Orthopaedic surgeons in 61 trusts and vascular surgeons in 47 contributed to both acute and elective diabetic foot care in the United Kingdom. ConclusionOrthopaedic foot surgery is a unique treatment.

Source link: https://doi.org/10.1302/2633-1462.38.BJO-2022-0025.R1


The Outcome of Surgical Treatment for the Neuropathic Diabetic Foot Lesions—A Single-Center Study

Diabetes has long been one of the most common u201cepidemicsu201d of our time, with the prevalence of diabetic foot problems on a continuum. The primary aim of this review was to outline the correct surgical treatment for the prone neuropathic diabetic foot; the secondary aim was to determine the risk factors associated with minor/major amputation, positive or adverse surgical outcomes. This is an observational, retrospective research published between 1 January 2018 and 31 December 2019, involving 251 patients from the Dr I. Cantacuzino Clinical Hospital in Bucharest with type II diabetes mellitus and neuropathic diabetic foot disease. Osteitis was predominantly associated with minor surgery, although the gangrene and the infected Charcot foot were both likely for significant injury with OR = 2. 230, 95% CI and OR = 5. 316, 95% CI.

Source link: https://doi.org/10.3390/life12081156


Microbiology of Diabetic Foot Infections in a Tertiary Care Hospital in São Paulo, Brazil

One of the causes of hospitalization in diabetic patients is diabetic foot infections, and empirical antibiotic therapy is required when this occurs. We've conducted a retrospective review of patients with DFI that necessitated hospitalization to determine microbiologic profile and susceptibility pattern of these infections. S. aureus and coagulase negative Staphylococci were the most common pathogen, followed by S. aureus and coagulase negative Staphylococci. With 76% susceptibility of P. aeruginosa to ceftazidime and meropenem, Gram-negatives' susceptibility profile was very good.

Source link: https://doi.org/10.3390/antibiotics11081125


Impact of acute hyperglycemic crisis episode on survival in individuals with diabetic foot ulcer using a machine learning approach

This study was retrospectively administered in a cohort study and sought to determine mortality risk factors in patients with DFUs-HCE. Methods27 inpatients with DFUs-HCE were compared to 93 inpatients with DFUs-HCE in a city designated emergency center between January 2016 and January 2021. ResultsMost patients with DFUs-HCE had diarrhea, acute kidney injury, and septic shock, whereas DFUs were more likely to have Dementia, acute kidney injury, and ulcer recurrence, whereas DFUs were more likely to have diabetesic peripheral neuropathy and ulcer recurrence. HCE significantly raised the risk of death in patients with DFUs than in patients with DFUs, but was unrelated to other confounding causes. Conclusions: ConclusionsBritishParticles: HCE was one of the most significant risk factors associated with all-cause mortality in patients with DFUs, according to the XGBoost simulator.

Source link: https://doi.org/10.3389/fendo.2022.974063


Ankle brachial indices and anaerobes: is peripheral arterial disease associated with anaerobic bacteria in diabetic foot ulcers?

Amputations from diabetic foot ulcers are recovering in lower extremity, and new biomarkers that predict wound healing are urgently needed. However, it is unclear if anaerobic markers are really a downstream result of peripheral arterial disease and ischemia. Here, we investigate the relationships between two measures of anaerobic bacteriau2014abundance and metabolic activityu2014and PAD. Methods: We designed a prospective cohort of 37 patients with baseline ankle brachial index findings. Anaerobic bacteria were characterized in two ways: DNA-based total anaerobic abundance using 16S rRNA gene amplicon sequencing and resulting summed relative abundance, and RNA-based metabolic activity based on bacterial read annotation of metatranscriptomic sequencing were measured in two ways: DNA-based total anaerobic abundance using 16S rRNA gene amplicon sequencing and resulting summed relative abundance and resulting summed relative abundance and metabolit bacterial-based on bacterial biochemical enzyme based on based on metabolit amplicon metabol metabolic activity based metabolit metabolic sequence metabolit biosynthesis based on metabolit based on based metabolit metabolic enzyme bacterial read annotation of metatranscriptomic sequence bacterial metabolit metabolic enzyme aeromic sequence and metabolit derived metabolit ampliconductomic sequence and aeromic sequence based on PAD diagnosis, ABI findings, and a dichotomous definition of mild ischemia based on ABI results were all applicable in three ways: PAD diagnosis, ABI findings, and a dichotomous definition of mild ischemia based on ABI results. Thus, anaerobic bacteria can have additional prognostic value in determining wound healing potential and should be investigated as potential molecular biomarkers for DFU outcomes.

Source link: https://doi.org/10.1177/20420188221118747


Efficacy and Clinical Value of Negative-Pressure Wound Therapy with Instillation (NPWTi) of Compound Phellodendron Liquid in the Treatment of Diabetic Foot Ulcer: A Prospective Cohort Study

paraphrasedoutput diabetic foot ulcer therapy with instillation of diabetic foot ulcers by detecting the growth of diabetic foot ulcers. To determine the efficacy and application value of compound Phellodendron liquid for negative-pressure wound therapy with instillation in diabetic foot ulcer therapy, diabetic foot ulcer therapy by observing the growth of diabetic foot ulcers. After undergoing treatment for ten days, 20 days, and 30 days, the positive proportion of bacterial culture in the CPL NPWTi group was dramatically reduced compared to the normal saline NPWTi group. The pain scores during dressing change, as well as the number of days in hospital in normal saline NPWTi were significantly lower than those in the CPL NPWTi group following therapy, were significantly lower than those in the CPL NPWTi group. Compound Phellodendron liquid NPWTi therapy can treat diabetic foot ulcers, providing a safe and effective method for treating diabetic foot ulcers.

Source link: https://doi.org/10.1155/2022/7540020


Difficulties in the Treatment of Diabetic Foot and Research Progress of Combination of Traditional Chinese and Western Medicine

Diabetes foot problems can be traced directly to peripheral arterial disease and/or sensory neuropathies affecting the diabetic foot; it is a long-term complication of diabetes. Foot soft tissue, bone, and joint system damage can result from peripheral neuropathy and peripheral vascular disease's swallowing. The diabetic foot care can be both difficult and chronic; it may include orthoses, surgery, antibacterial drugs, and topical dressings. Traditional Chinese medicine has a number of ways for the treatment of diabetic foot, which can be divided into internal therapy and external therapy of TCM. Modern medicine in conjunction with herbal therapy can greatly improve diabetic foot prognosis, according to several studies. This report outlined the difficulties in the treatment of diabetic foot and the recent research results in combining Chinese and Western medicine in the treatment of diabetic foot.

Source link: https://doi.org/10.1155/2022/9449427


Microbiological profile of diabetic foot infections and the detection of mecA gene in predominant Staphylococcus aureus

BACKGROUND Diabetes mellitus is a significant health condition that is quickly expanding worldwide. Staphylococcus aureus, a pathogenic bacterium that has a variety of drug-resistant strains, is a pathogenic bacterium. Patients with diabetic foot ulcers - in individuals with uncontrolled blood sugar levels - have been isolated from patients with diabetes foot ulcers, resulting in elevated morbidity and mortality around the world. Diabetes foot infections are caused by the prevalence of drug-resistant Staphylococcus aureus in diabetic foot infections. At a tertiary care hospital, an epidemiological investigation was carried out, and 300 pus samples were obtained from wounds, absces, skin, and soft tissue lesions of patients with type II diabetes with foot ulcer infections. Staphylococcus aureus isolates were resistant to methicillin in a total of 13 isolates. MecA genes account for over 58% of all methicillin-resistant Staphylococcus aureus isolates, according to this report.

Source link: https://doi.org/10.18051/UnivMed.2022.v41.121-128


Ultrasound Guided Femorosciatic Block for Diabetic Foot Ulcer in a Psychiatric Patient with Sepsis, Anaemia and Coagulation Defect

Diabetes mellitus complications include macrovascular, microvascular, electrolyte, and metabolic derangements. Foot ulcer is a common complication of diabetes mellitus with deranged Blood Sugar Levels, and it needs to be removed or amputation.

Source link: https://doi.org/10.18502/aacc.v8i4.10184


Sequelae of Hospitalization for Diabetic Foot Ulcers at LASUTH Ikeja Lagos: A Prospective Observational Study

Abstract:Diabetic foot ulcers are a common sequelae of diabetes that cause debilitating effects on the sufferer. paraphrasedoutput:MethodsA single-center prospective observational study investigated the evolution of certain aspects of epidemiology and the current clinical consequences of DFUs. paraphrasedoutput:ResultsTotal medical admissions during the study period were 2288, 350 were DM related, out of which 112 were eligible for DFU. Of total DM admissions, 32% were for DFU. The mean age of the study subjects is 5 years to 87 years, and it is from 35 years to 87 years. The mean duration of DM is 8. 32 years, not 17. 27 years as of Jan. 28. At presentation, the average duration of ulcers was 72. 0 days, 1138. 13 days. The majority of patients were diagnosed with severe ulcers, but Wagner grade four was the most common. Concomitant heart failure 404-68, 4. 856, 0. 489-4. 856, the cause of amputation. Concomitant heart failure was a cause of amputation.

Source link: https://doi.org/10.3389/fcdhc.2022.889264

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions