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Diabetes Type 1 - Wiley Online Library

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Last Updated: 28 June 2022

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Incidence of type 1 diabetes in children in Dominican Republic, 2010–2019: A national collaborative study

There are no recent studies on type 1 diabetes in children in the Dominican Republic. All new T1D diagnoses between 2010 and 2020 were obtained from the four organizations caring for children with T1D. Using Poisson regression, the trend and the effects of T1D prevalence were determined as well as age and sex. A total of 1224 new cases of T1D were reported as of May 15y, a 102-day standard deviation of 122 u00b1 12 cases per year; mean 122 u00b1 standard deviation 122 0 U00b1 average deviation 122 0 cases per year. Age at T1D diagnosis was 8. 8 years old (2007), with a significant female preponderance. When evaluating the age group in 102013-14 y, the incidence was consistently high in 10u201314 years, and lowest in 0u20134 y in all study years. The mean crude T1D annual incidence in the 100,000 population was 4. 3 percent. The prevalence of T1D in children under the age of 15 in the Dominican Republic is relatively low, but it is consistent with the scant results from other regions in the region.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/pedi.13380


The missing heritability in type 1 diabetes

Type 1 diabetes is a difficult autoimmune disease characterized by an absolute lack of insulin. T1D-positive loci have been found in more than 60 of the heritability's disease-related loci, accounting for over 80%-u201085% of the heritability. While the triad between suspected hereditability and true heritability in T1D is small compared to that among other common traits and disorders, further elucidation of T1D genetics may be able to gain new insight into the disease's pathogeny and therapeutic targets.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/dom.14777

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions