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Developmental Biology - Wiley Online Library

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Last Updated: 18 June 2022

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Changing the drug development and therapeutic paradigm with biologic drug combinations and bispecifics: How to choose between these two approaches?

"Rational design of combinations and dual-u2010targeting strategies that consider disease complexity have the ability to enhance diagnostic accuracy and safety, to extend clinical life, and minimize clinical resistance mechanisms. " Here we discuss case studies of BsAbs and biologic combinations that have been approved by health authorities and now drug manufacturing considerations when deciding between these two options. Future introduction of biologic triple combinations and BsAbs combinations with other biologics may exacerbate drug manufacturing issues, as well as providing patients with more effective treatment options.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/cts.13345

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions