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Cushing's Syndrome - Astrophysics Data System

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Last Updated: 13 October 2021

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Machine-learning based prediction of Cushing's syndrome in dogs attending UK primary-care veterinary practice

Cushing's syndrome is an endocrine condition in pet dogs that adversely affects on the quality-of-life of affected animals. Pets presumed of having Cushing's syndrome were included in the evaluation and identified based on their final reported diagnosis within their medical records. The LASSO punished regression design suggested the most effective overall performance when applied to the test set with an AUROC = 0. 85, level of sensitivity = 0. 71, uniqueness = 0. 82, PPV = 0. 75 and NPV = 0. 78. New approaches using these approaches could sustain medical decision-making and contribute to enhanced medical diagnosis of Cushing's syndrome in pets.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..11.9035S/abstract


Central serous chorioretinopathy in active endogenous Cushing's syndrome

Multiple case collection have provided evidence for a relatively high incidence of central serous chorioretinopathy in patients with active Cushing's syndrome. We define the ophthalmological standing thoroughly of successive patients with active endogenous CS in this prospective cohort research. Eleven CS patients with active hypercortisolism were included. 2 other patients revealed CSC-like problems: an independent pseudovitelliform sore on OCT and hyperfluorescent changes on fluorescein angiography in one individual, and unilateral leak on fluorescein angiography in the various other patient. Retinal abnormalities looking like CSC may be a lot more usual than formerly believed in patients with active CS, and may exist even in patients without visual issues. Medical professionals should have a low threshold for ophthalmological examination in case of a CS patient with aesthetic symptoms since there might be healing possibilities to avoid vision loss.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..11.2748B/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions