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Cryoglobulins - Europe PMC

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Last Updated: 29 April 2022

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Practical Details for the Detection and Interpretation of Cryoglobulins.

Background Cryoglobulins are immunoglobulins that precipitate at low temperatures. In any laboratory that has a 37 °C incubator and temperature-controlled centrifuge, the first step of detection of cryoglobulins can be carried out. Characterization includes immunoglobulin typing for the determination of cryoglobulins and potential underlying disease; measurement of serum complement; and determination of serum complement, which is useful for diagnosis. Summary These practical guidelines will be helpful in the proper detection of cryoglobulins, an important first step in the diagnosis of cryoglobular vasculitis, a rare but severe clinical manifestation of cryoglobulins.

Source link: https://europepmc.org/article/MED/34718470

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* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions