Advanced searches left 3/3

Cortisol - U.S. Department of Veterans Affairs

Summarized by Plex Scholar
Last Updated: 19 September 2022

* If you want to update the article please login/register

Imaging brain cortisol regulation in PTSD with a target for 11β-hydroxysteroid dehydrogenase type 1.

BACKGROUNDInvestigations of stress dysregulation in posttraumatic stress disorder have primarily centered on peripheral cortisol, but no have investigated cortisol in the human brain. paraphrasedoutput:RESULTS: This research used positron emission tomography to photograph 11u03b2-HSD1 as a putative brain cortisol marker in PTSD. METHODS: This research showed that nineteen people with PTSD and 17 healthy, trauma-exposed controls underwent PET imaging with [18F]AS2471907, a radioligand for 11u03b2-HSD1 for PTSD, was considerably higher in the PTSD group compared tomograph deti CONCLUSION: In a PTSD subset, a higher 11u03b2-HSD1 occurrence was linked to increased availability of translocator protein, a microglial marker, causing reduced PTSD symptoms in the PTSD group.

Source link: https://doi.org/10.1172/JCI150452

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions