* If you want to update the article please login/register
The narrowed vessel locations are bridged, with catheterization widening of the narrowed / blocked coronary vessel and stent or bypass surgery. The "German National Disease Management Guideline on cCHD" aids physicians in determining which therapy is most appropriate for the patient's vascular disease and potential concomitant diseases. The REVASK program seeks to determine whether or not the collaboration of cardiology and heart surgery specialists in so-called "heart teams" influences the decision on therapy. Doctors and patients will be interviewed about how the treatment decision was made and how both sides are satisfied with the outcome of the treatment and the decision for this purpose. In addition, claims data from several German health insurance companies will be analyzed.
Source link: https://clinicaltrials.gov/ct2/show/NCT04599361
The new report will determine the likelihood of an intensive lifestyle intervention to reverse newly diagnosed prediabetes in patients with coronary heart disease who would otherwise begin a standard cardiac rehabilitation program. The DIABEPIC prevent 1 survey, which is a single-arm, open-label research aimed at demonstrating the effectiveness of an intensive multidisciplinary stepwise intervention in newly diagnosed prediabetic and coronary heart disease patients, ultimately aiming to reduce prediabetes. The aim of this first research is to develop and iteratively enhance participant recruitment and adherence strategies for a prospective future randomized controlled trial.
Source link: https://clinicaltrials.gov/ct2/show/NCT05459987
To minimize the number of times people come close to in contact with others or gathering in large groups, there is a significant need for innovative approaches to deliver CR services other than frequent face-to-face sessions at the center-based CR. The purpose of this proposed research is to investigate the effects of technology-assisted interventions in hybrid heart disease treatment among the coronary heart disease patients. The objectives are as follows: to determine the effects of TecHCR on exercise related to fitness; to determine the effects of TecHCR on exercise motivations; to determine the consequences of TecHCR on exercise capacity; and to determine the effects of TecHCR on obesity and depression. The patients will be the participants of their first follow-up by the physicians in cardiac rehabilitation clinic's first follow-up, followed by a monthly recap. The intervention group will receive 3 times supervised exercise in the center, as well as weekly upload of CR education on WhatsApp for six weeks. The results will be considered significant by a p value of 0. 05, which will be used to record and analyze data. IBM Social Package Statistical Software SPSS version 26. 0 with a p value of 0. 05 would be considered significant in the analysis.
Source link: https://clinicaltrials.gov/ct2/show/NCT04862351
They contributed to more than 4 million deaths in Europe in 2014, more than 4 million deaths in Europe, and coronary heart disease alone accounts for nearly 1. 8 million deaths, or 20% of all deaths in Europe. However, cardiovascular disease and, in particular, coronary heart disease deaths have decreased in recent decades. Even when other risk factors are controlled, several research have shown that a poor quality of life related to health is a predictor of morbidity and mortality in patients with coronary artery disease. Depression, anxiety, dyspnea, and angina pectoris have all been cited as factors that may influence patients with coronary artery disease, including depression, anxiety, dyspnea, and angina pectoris. Patients with cardiovascular disease: Depression and anxiety were both negatively associated with poor health-related quality of life. When the quality of life is assessed in patients with coronary heart disease, it is therefore important to monitor these factors. The clinician and the patient may have differing questions about quality of life: the clinician and the patient often have conflicting questions: what the clinician considers to be a "successful procedure" is not always recognized by the patient as such. Many patients find that the quality of life of the additional years of life acquired is just as important as the longevity, so today's medicine aims to raise the number and quality of life of the additional years of life acquired. The measurement of health-related quality of life should be integrated into the regular clinical practice of coronary heart disease management to ensure this improvement.
Source link: https://clinicaltrials.gov/ct2/show/NCT03904589
The American Heart Association and the American College of Cardiology Foundation both agreed that lifestyle changes, including physical activity, was the class one-level recommendation for secondary prevention and risk reduction therapy for patients with CHD. The analysis of physical fitness and confidence in exercising exercise for patients with CHD will help healthcare professionals develop and implement the right strategy to help patients' physical fitness and physical fitness improve their patients' health. With increasing morbidity and mortality from CHD, particularly in low and middle-income countries, secondary prevention, such as exercise-based cardiac rehabilitation, plays a key role in improving CHD patients' prognosis. Participants will be patients admitted to the Teaching Hospital Batticaloa, Sri Lanka's CHD unit and medical wards for the first time revealed by electrocardiogram with ages 18 years or older, able to read and speak Tamil, willing to attend clinic follow-up, obtain medical clearance from a cardiologist to administer the exercise, and be able to read and give informed consent, and be able to recognize and give informed consent. The statistical Package for Social Science version 22. 0 software will be used to analyze the results, but the p-value less than 0. 5 will be considered significant. In a low-resource setting, the findings from this research may be able to promote healthy lifestyle habits among CHD patients.
Source link: https://clinicaltrials.gov/ct2/show/NCT05051774
According to the time of their participation, healthy volunteers will be required to perform either a non-contrast MRI or a contrast-enhanced MRI of the coronary artery, depending on the subject's need for growth. Healthy volunteers will eventually be invited to participate in a non-contrast or contrast-enhanced MRI for examining the image quality associated with each acquisition module of the newly developed procedure and motion artifact associated with motion compensation policies, according to If all the safety requirements are fulfilled, a total dose of up to 0. 2 mmol/kg of a gadolinium-based contrast agent will be administered intravenously to subjects undergoing comparison.
Source link: https://clinicaltrials.gov/ct2/show/NCT03504956
FFR measurements from coronary computed tomography angiography images have been used with excellent diagnostic fidelity in comparison to invasive FFR, thanks in recent advances in computational fluid dynamics. FFRCT can also help guide revascularization in a safe way for the patient with a FFRCT > 0. 80 from invasive angiography. In non-detection lesions, numerically non-significant lesions, computational fluid dynamic simulations in lieu of CT plaque measurements may be able to predict which lesions will become flow-limiting, causing clinical events in the future. This research will look at disease progression in intermediate lesions using FFRCT for two years to see if CT characteristics could help to identify lesions that are more susceptible to FFR decline.
Source link: https://clinicaltrials.gov/ct2/show/NCT04052256
In the Chinese population, both scan and injection protocols are tailored to the individual patient. The primary goal is to prospectively assess the diagnostic quality of a previously published personalized scan and CM injection CCTA protocol. Secondary aim: To determine the radiation dose and contrast media dose of this personalized approach to CCTA in a Chinese patient population. Care kV is a software that gathers data about the patient's own attenuation values/ x-ray absorption during a so-called scout scan. This includes both a variable tube current along the patient's z-axis and an individual tube voltage. Using the Personalized Patients Protocol Technology (PCT) software included in the high-pressure injector, the CM injection parameters are calculated in accordance with patient and examination-related settings. Individualized contrast injection protocols are calculated by P3T software. Then, the injection duration is determined based on the duration of the scan and minimum injection time. For higher flow rates, the antecubital vein's An 18G or 20G venous access in the antecubital vein is preferred. Test bolus + saline flush, next CM bolus and saline flush 40 ml, plus test bolus + saline flush. The test bolus is followed by 40ml of saline flush at the same flow rate. Given the estimated non-diagnostic rate of around 5%, the 95% CI of non-diagnostic rate with 300 sample size is [2. 8 percent, 8. 1%]. Although there is no hypothesis test planned for this study, the findings from a recent published review of liver CT personalized scan and injection protocols help ensure that the current study has the correct sample size.
Source link: https://clinicaltrials.gov/ct2/show/NCT05497466
The expense of medical services in the United States far outstrips that of other advanced economies, and it continues to rise at a rate that is unacceptable to our society, owing in large part to rising costs of new imaging equipment and novel medications. Cardiac's positron emission tomography imaging is a novel new technology for the noninvasive detection of inflammatory coronary ischemia in patients with low to moderate risk chest pain or its equivalent. About 6000 clinical cardiac PET scans per year are conducted by Intermountain Medical Center. Coronary artery calcium measurement is a sensitive indicator of coronary atherosclerosis. ACCURATE will determine whether a CAC-first plan, which was administered routinely in symptomatic patients presenting for examination of possible coronary artery disease before the cardiac PET stress test, could be used as a gatekeeper for the upcoming rubidium-PET stress perfusion scan and be a major cost saver without adversely affecting patient care or outcomes. Many with CACS 22641 will be granted and randomized to either a heart PET stress test instrument design or a non-PET-driven medical care program, according to ACCURATE's CACSu22641. Subjects who were randomly assigned to the cardiac PET stress testing program will receive appropriate post-care based on the findings of the cardiac PET scan findings. The purpose of this report is to determine whether PET stress test strategy will result in a decrease in major adverse cardiac endpoints without exceeding $100,000 per year compared to a CAC-first initiative for screening suspected/possible coronary artery disease.
Source link: https://clinicaltrials.gov/ct2/show/NCT03972774
The FUSE-HEART study is a prospective, observational, single-center cohort study that will be carried out in the Laboratory of Advanced Research in Cardiac Multimodal Imaging, University of Târgu, Romania. The study will include 100 participants with coronary lesions as portrayed by the CCTA examination. Patients with anatomically significant coronary lesions on native coronary arteries, or patients surviving a severe myocardial infarction, whether revascularized or not, will be included in the study population. Positive remodeling, napkin-rink sign, presence of low density plaque or spotty calcium within the plaque will be determined for each plaque by one point in the following vulnerability indicators: positive remodeling, napkin-rink sign, or spotty calcium within the plaque. Following the 3D fusion of the photographs of the coronary tree with the images showing wall motion, the connection between plaque morphology and composition on one hand, and wall motion in the corresponding distribution territory of the coronary artery will be investigated based on fused models. Primary aim: To investigate the effect of a coronary artery stenosis on myocardial function and viability, based on advanced fusion imaging techniques developed from CCTA. Secondary: To investigate the relationship between atheromatous plaques located in a coronary artery and myocardial ischemia in the territory irrigated by the same coronary artery. u2022 Baseline - obtain and sign consent from the participant on the study consent form. u2022 Baseline - Obtaining and monitoring consent from the participant on the study consent form.
Source link: https://clinicaltrials.gov/ct2/show/NCT04680689
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions