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Colorectal Cancer - MedlinePlus Genetics

Summarized by Plex Scholar
Last Updated: 19 January 2023

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Lynch syndrome

People with Lynch syndrome are also at an elevated risk of stomach, small intestine, liver, gallbladder ducts, urinary tract, and skin cancers. Because of these cancers of the female reproductive system, women with Lynch syndrome have a greater risk of developing cancer than men with the condition. Noncancerous growths in the colon may occasionally have colon polyps that are not related to Lynch syndrome.

Source link: https://medlineplus.gov/genetics/condition/lynch-syndrome


Familial adenomatous polyposis

People with the atypical adenomatous polyposis syndrome may begin to experience multiple noncancerous rises in the colon as early as their teenage years. 39 years old is the average age at which an individual develops colon cancer in classic familial adenomatous polyposis. attenuated familial adenomatous polyposis onset is 55 years old. Polyps increase with age in people with classic familial adenomatous polyposis, and hundreds to thousands of polyps can develop in the colon. People with colon polyps as well as colon polyps growths outside of the colon are often described as having Gardner syndrome. A milder form of familial adenomatous polyposis, autosomal recessive familial adenomatous polyposis, has also been identified. People with the autosomal recessive disorder have fewer polyps than those with the classic version.

Source link: https://medlineplus.gov/genetics/condition/familial-adenomatous-polyposis


Constitutional mismatch repair deficiency syndrome

Constitutional mismatch repair deficiency syndrome (Certism) is a rare condition that significantly increases the risk of acquiring one or two forms of cancer in infants and young adults. Nearly all people with CMMRD syndrome develop cancer before age 18, mostly in late childhood. About 20 to 40% of people with CMMRD syndrome who have cancer will have another cancer later in life, according to estimates. People with CMMRD syndrome may experience multiple noncancerous growths in the colon that are likely to become cancerous over time. Non-Hodgkin lymphoma, the most common blood cancer in CMMRD syndrome, affects white blood cells, is the most common blood cancer in CMMRD syndrome. CMMRD syndrome sufferers have facial features similar to those that occur in a condition called neurofibromatosis type 1. The birth of CMMRD syndrome is also misdiagnosed with neurofibromatosis type 1.

Source link: https://medlineplus.gov/genetics/condition/constitutional-mismatch-repair-deficiency-syndrome

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions