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Chronic Pain - Crossref

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Last Updated: 26 March 2022

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Treatment of chronic pain by using intrathecal drug therapy compared with conventional pain therapies: a cost-effectiveness analysis

Patients suffering from persistent low back pain triggered by failed back syndrome were compared to the cost-effectiveness of intrathecal drug therapy in patients suffering from chronic low back pain related to failed back syndrome. In this report, the authors tabulated actual costs in a series of patients receiving IDT within the Canadian health care system and compared them to control groups in the same environment. Patient responses on the Oswestry Pain Questionnaire were used to determine the effects of therapy on QOL. Following this time point, managing patients with CPT became the more expensive treatment option for the remainder of the follow-up period. Patients in the IDT group had a 27 percent increase in their health, relative to a 12% rise in the control group. The Oswestry Disability Index reported a 27 percent increase for patients in the IDT group, compared to a 12% increase in the control group.

Source link: https://doi.org/10.3171/jns.2002.97.4.0803


Activation of the anterior cingulate cortex by thalamic stimulation in patients with chronic pain: a positron emission tomography study

The authors compared positron emission tomography photographs obtained before, during, and after DBS in five patients with persistent pain. During PET scanning, two of the five patients reported significant DBS-induced pain relief, while PET scanning was not reported, and the remaining three patients did not experience any analgesic effect of DBS during scanning. During DBS's 40 minutes, an anterior ACC activation was sustained, whereas a more centralized ACC activation occurred at a time after the onset of DBS, but these activations were not dependent on the degree of pain relief that was reported during DBS.

Source link: https://doi.org/10.3171/jns.2000.92.1.0064


Cancer pain relief using chronic morphine infusion

Fourteen patients were implanted with drug pumps in order to relieve pain due to cancer's pain. In seven of the patients, a new programmable pump was used, and a constant infusion unit was used in the remaining seven patients.

Source link: https://doi.org/10.3171/jns.1984.61.2.0302


Pain relief from peripheral conditioning stimulation in patients with chronic facial pain

In a prospective study, 50 consecutive patients, referred to a pain treatment unit for surgery to treat various aspects of facial pain, were all given transcutaneous nerve stimulation therapy and followed for two years. When pharmacological therapy falls, particularly in the elderly and in patients with atypical facial pain, it is concluded that TNS therapy is a safe alternative to surgery.

Source link: https://doi.org/10.3171/jns.1984.61.1.0149


Spinal cord stimulation in management of chronic pain

109 patients with persistent pain underwent spinal cord stimulation at the authors' clinic between 1978 and 1986 as part of their pain management program. SCS results in these patients at the end of the test period and at the most recent follow-up examination are examined in relation to their pain etiology. The etiology of five patients' pain was unclear. No clinically appropriateness was found for SCS in either cancer pain or in central deafferentation syndrome types of pain.

Source link: https://doi.org/10.3171/jns.1989.70.4.0519


Effects of back exercises versus transcutaneous electric nerve stimulation on relief of pain and disability in operating room nurses with chronic non-specific LBP: a randomized clinical trial

Abstract Background The low back pain is one of the most common musculoskeletal disorders related to working. With LBP, the present study was designed to determine the effect of two therapeutic methods of back exercises and transcutaneous electrical nerve stimulation on the disability and pain of operating room nurses. Methods The clinical trial of forty-four eligible operating room nurses with a regular nonspecific LBP were randomly assigned to back exercises or TENS groups by a randomization system. The McGill pain questionnaire for back pain and the Oswestry disability questionnaire for disability diagnosis were completed right away before and after the interventions. Significant decreases in the pain score and disability scores were revealed in the back exercises group after the intervention compared to the baseline, according to the researchers. After adjusting for the baseline results, the TENS group experienced a significantly higher pain score decline than the back exercises group.

Source link: https://doi.org/10.1186/s12891-022-05227-7


Electrical stimulation of the brain in treatment of chronic pain

During 1978 to 1983, forty-eight patients underwent electrical stimulation of the brain for chronic pain relief. 4. 5 years before treatment was considered a risk of pain. Patients underwent pain management in a multidisciplinary pain center, extensive psychological and psychiatric investigation, and evaluation of pain response to intravenous delivery of placebo, morphine, and naloxone before deciding on this procedure. Patients in seventy-two percent of patients reported complete or partial pain relief. Electrical stimulation of the brain provides a safe and fast way for the management of chronic pain in properly selected patients who are unresponsive to other forms of therapy.

Source link: https://doi.org/10.3171/jns.1985.62.3.0389


A comparison of intrathecally administered narcotic and nonnarcotic analgesics for experimental chronic neuropathic pain

Tizanidine increased to maximum levels in a dose-dependent manner, causing paw removal and shortened the duration of limb withdrawal from both normal-temperature and cooled floors in a dose-dependent manner. Tizanidine had virtually no effect on the latency of paw withdrawal from a noxious heat stimulus, according to the manufacturer. These results show that intrathecal tizanidine can be more specific than morphine in reversing neuropathic pain syndromes and hypertension, and may be more useful in the treatment of patients with these medical syndromes.

Source link: https://doi.org/10.3171/jns.1995.82.4.0595


Electrical stimulation of the trigeminal nerve root for the treatment of chronic facial pain

Between March 1990 and December 1992, 23 patients with persistent intractable facial pain related to various types of injury to the trigeminal nerve or nerve root underwent surgery using an electrical stimulation device to alleviate their pain. During a period of trial stimulation, at least 50% pain relief was felt, but the electrode was not fully embedded in the device, resulting in a complete absence of a fully implanted pulse generator. Six patients reported nearly complete pain relief, while six others reported at least 50 percent decrease in pain intensity using a visual analog scale over a 24 month mean follow-up period. In a substantial number of patients, chronic facial pain related to injuries to the trigeminal nerve root appears to be a fast and effective method for relieving chronic facial pain related to inflammation of the trigeminal nerve root.

Source link: https://doi.org/10.3171/jns.1995.83.1.0072


Chronic stimulation of the Kölliker-Fuse nucleus region for relief of intractable pain in humans

Chronic electrical stimulation in the periventricular or periaqueductal gray matter regions and the thalamic somatosensory relay nuclei aids in long-term pain relief in about half of patients with chronic pain persistency to other conservative and/or surgical treatments. In three of the six patients, excellent pain relief was obtained by stimulation in the periaqueductal/periventricular grey matter region or the somatosensory thalamic nucleus stimulation alone or in combination with stimulation in the periaqueductal/periventricular gray matter region.

Source link: https://doi.org/10.3171/jns.1992.76.6.0979

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions