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Chronic Pain - ClinicalTrials.gov

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Last Updated: 26 April 2022

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Sublingual Cannabidiol for Chronic Pain

For thousands of years, Cannabis sativa has been used medicinally to treat a variety of diseases. MMJ cannabinoid constituent quantities and ratios can vary drastically, from high THC products with little CBD to 1:1 ratios of THC to CBD, to high CBD products with little THC. Chronic pain is one of the most common MMJ use indicators, and several studies have revealed that MMJ and its derivatives may have analgesic and anti-inflammatory properties, indicating that particular cannabinoids may have the ability to treat chronic pain. No clinical trials have been done to determine the effects of a high-CBD, low-THC drug for chronic pain, to date.

Source link: https://clinicaltrials.gov/ct2/show/NCT03984565


Self-Management of Chronic Pain Using a Digital Pain-Management Tool.

Chronic pain is an epidemic affecting both Europe and the United States, with an estimated 90 million people in Europe and 100 million in the United States, or 20-30% of the adult population around the world. Chronic pain is a growing health issue in both Europe and the United States, with an estimated 90 million people affected in Europe and 100 million in the United States, representing 20-30% of the world's adult population. Chronic pain is a disorder that persists for at least three to six months, after the normal healing period of an injury. As measured by PROMIS pain interference 6a, patient taken part of multi modal care services such as acceptance and commitment therapy, show that less than half of the patients have a decrease in the pain level below 1 percent, while 95% have no effect, and 9 percent have an elevated level of pain after going through the program. Patients who follow their standard treatment regimen provided by the Pain Clinic and with the addition of using a web browser for increased self-management of pain, we'll here compare the quality of life. Hence, self-management of pain Increased function in daily life with the best possible variety and participation degree Decreased pain experience Improved pain quality of life Decreased pain experience Decreased pain perception Hence self-management of pain Increased pain with increased visibility and participation level.

Source link: https://clinicaltrials.gov/ct2/show/NCT04628650


Self-management of Chronic Pain Through the Use of the Digital Tool PainDrianer

Chronic pain is an epidemic affecting both Europe and the United States, with an estimated 90 million people affected in Europe and 100 million Americans in the United States, or 20-30% of the world's adult population. Chronic pain is a disorder that persists for at least six months, after the normal recovery period of an injury. According to PROMIS pain interference 6a, the study's aim is to find out how the use of a digital pain coach, which is based on artificial intelligence that improves pain management, would reduce pain and thus raise QoL among chronic pain patients. This report will compare the improvement of quality of life in patients with a decrease in pain interference, measured by PROMIS, with the addition of the use of a web browser for enhanced pain control. The present investigation seeks to determine the effect of including digital technology as an add-on to standard medical and rehabilitation at the clinic's rehabilitation program, as well as measuring the effects it has on: Reduced pain interference Improved pain management Long-term pain management and its consequences. Hence self-management of pain. Hence, increased pain relief in daily life with the highest degree of involvement and involvement. Decreased pain experience Decreased pain experience Decreased pain experience.

Source link: https://clinicaltrials.gov/ct2/show/NCT05213468


Auricular Acupuncture for Chronic Pain and Insomnia: a Randomized Clinical Trial

History: Around 1. 6 million adults in the United States use complementary and alternative or integrative medicine therapy for pain and insomnia. However, only a handful of studies have looked at the use of auricular acupuncture in patients with persistent pain and insomnia. Over an 8-day study period, the aim: To determine the acceptability and acceptability of AA and to determine the effectiveness of AA on pain severity score, pain interference score, and insomnia. On day 4, 45 people who fulfilled the eligibility requirements and signed the pledge were randomly assigned to either the AA group or the usual care control group. Insomnia Severity Index for insomnia and pain severity, as well as the Insomnia Severity Index for insomnia. Results: The use of the standard AA protocol in the AAG resulted in a significant decrease in pain severity and interference scores both within and between-groups, as well as within-group reductions in pain severity and interference scores when compared to the CG.

Source link: https://clinicaltrials.gov/ct2/show/NCT03503695


Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

An immersive, beautiful, and multisensory stimulation can be used to reduce pain and suffering by using VR. As two methods that look at pain modulation, the investigator will investigate the behavioral and neural mechanisms of active VR against sham VR. The investigators will determine how the opioid tone affects VR-induced hypoglycia in TMD participants using VR, tonic painful stimulus, and naloxone administered intranasally with established mu-opioid receptor occupancy in Aim 1 to determine how the opioid tone affects VR-induced hypothea.

Source link: https://clinicaltrials.gov/ct2/show/NCT04851301


Mechanisms of Psychosocial Treatments on Opioid Use in Chronic Pain

Participants wear an activity monitor for about two and a half months, beginning two weeks before treatment begins. Extended Assessments During the course of the study, participants will complete four extended assessments with a research staff member in addition to the study. The first interview is completed before hospitalization begins; the second is completed after treatment concludes, the third is completed three months after diagnosis has been completed, and the fourth and final are completed six months after treatment ends. The final two extended reports can be completed either verbally over the phone or online by a research associate. Online Surveys Two weeks before treatment begins, participants begin conducting brief online surveys twice a day. During the 2. 5-month Monitoring Period, participants wear an activity monitor 24 hours a day. Like a wristwatch, the activity monitor is worn on the non-dominant wrist. Patients are randomly assigned to one of the three treatment groups. The treatment consists of eight group therapy sessions carried out remotely over a videoconferencing service. For each group therapy session, participants will be required to use a video camera and audio through either a microphone or phone. Participants will be educated about pain, discussing the effects of pain, and finding new ways to handle it in the hopes of reducing pain and its effects. Participants also received a treatment workbook with materials to refer to and discuss during the group sessions, as well as additional reading between sessions.

Source link: https://clinicaltrials.gov/ct2/show/NCT03916276


Empower Opioid Misuse Theranova Study for Veterans With Chronic Pain

This pilot study will explore the possibility, acceptability, and preliminarily assess the efficacy of peripheral nerve stimulation with the Empower Neuromodulation System on lowering opioid use and use, as well as pain relief. Opioid prescribing for chronic pain has risen steeply over the past few decades, with severe public health implications, including increased rates of opioid misuse and overdose deaths. Participants will be surveyed on Days 1-7, and on Days 8-21, participants will receive daily nerve stimulation therapy.

Source link: https://clinicaltrials.gov/ct2/show/NCT04184362


Impact of Yogotherapeutics in Consultation on Chronic Pains' Patients

More and more studies are now investigating yoga's positive effects, whether it is on stress or on the reduction of symptoms of depression, immunity enhancement, or pain. No study on the effects of yoga for analgesic therapy has been carried out in France to our knowledge.

Source link: https://clinicaltrials.gov/ct2/show/NCT05160181


Home-Based Intervention for Chronic Pain in Adults With Sickle Cell Disease (HIPAS)

Non-pharmacological, home-based programs are urgently needed to help with chronic pain management due to the high pain burden associated with SCD and the existing health ineffective pain management. In this report, the investigators will use a single-site, 8-week randomized clinical trial to find out if a home-based, pain self-management service for chronic pain in Black adults with SCD. Participants will complete questionnaires and a pain diary, use the pain management software at home, and conclude a qualitative interview or focus group session. This is the first randomized clinical trial that looks at a virtual reality, home-based pain self-management scheme for chronic pain in adults with SCD. According to this report, it is the first significant step in producing a culturally tailored, non-pharmacological, home-based, chronic pain management service for Black adults with SCD who can be used alongside regular SCD care.

Source link: https://clinicaltrials.gov/ct2/show/NCT04906707


Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord

Chronic exhaustion and fibromyalgia syndrome are two common musculoskeletal pain disorders that mostly affects women. So far, no consistent soft tissue abnormalities have been found in these patients. Using a numerical scale, patients and normal control subjects will verbally rate the severity of late sensations elicited by each stimulus. These patients' results, at least partially, resulted from exaggerated production of central N-methyl-D-aspartate receptors as a result of increased intake from deep tissue-supplying deep tissue. With subsequent signs of hypertension and allodynia, a temporal summation of second pain could lead to central sensitization. The results of pain improvement with repetitive experimental stimulation will be used to track their ratings of repeated experimental stimuli and FM patients, as well as the resulting pain improvement. The completion of this research will provide a new means for the analysis of chronic pain/fatigue syndrome and their response to therapy.

Source link: https://clinicaltrials.gov/ct2/show/NCT03075254

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions