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Chronic Kidney Disease - PLOS

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Last Updated: 15 January 2023

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Pharmaceutical care program for patients with chronic kidney disease in the community pharmacy: Detection of nephrotoxic drugs and dose adjustment. Viability study

Introduction: Chronic kidney disease is a common health issue. Diagnosis of CKD is also vital to avoid nephrotoxic drugs and to adjust the doses of other medications that may be affected. Objective: To find and cite the primary care physician patients with low estimated glomerular filtration rate who use nephrotoxic drugs or who may require a dose adjustment. This amounts to 2. 3% of medications administered by patients with an eGFR less than 60 ml/min/1. 73 m2. Patients with poor eGFR in 9 patients were treated by 29 patients and a change in treatment was made in nine patients, accounting for 4. 6 percent of the total number of patients in the study and 10% of the patients with low eGFR. Conclusion: Point-of-care testing for kidney function in a pharmacy setting is feasible and has found a significant number of patients with eGFR under 60 ml/min/1. 73 m2.

Source link: https://doi.org/10.1371/journal.pone.0278648


An exploration of under-registration of chronic kidney disease stages 3–5 in Belgian general practices using logistic regression

Background: Early detection and treatment of chronic kidney disease early can help prevent further deterioration and complications. This study was designed to explore the prevalence of unregistered CKD stages 320135 in a Belgian General Practitioner population, determine risk factors for under-registration, and assess diagnostic delay. The study used INTEGO data from 2018 for all patients u226518 years old>. CKD was described as two separate eGFR laboratory measurements at least three months apart during the baseline period. During the first eGFR survey and up to six months after the second eGFR in the EHR, the registered CKD was defined by a documented diagnosis of CKD during the u226512-month lookback period. Conclusion: The percentage of patients without a licensed CKD code in the EHR was high. The differences between registered and unregistered patients make it difficult to register in the EHR.

Source link: https://doi.org/10.1371/journal.pone.0279291


Chronic kidney disease in nonalcoholic fatty liver disease at primary healthcare centers in Korea

Background: With the increasing prevalence of nonalcoholic fatty liver disease and chronic kidney disease in young populations, the prevalence rates of nonalcoholic fatty liver disease and chronic kidney disease is expected to rise. Given the effects of coexisting NAFLD and CKD on morbidity and mortality rates, screening methods for groups at high risk of CKD are required in community-dwelling individuals with NAFLD. In asymptomatic patients with NAFLD at primary healthcare centers in Korea, the aim of this research was to establish the incidence and distribution of CKD in NAFLD, as well as the risk factors for CKD and liver fibrosis. In NAFLD, multivariable logistic regression studies were conducted to determine the risk factors for CKD and liver fibrosis. Conclusion: The presence of NAFLD and liver fibrosis were independent risk factors for CKD, but NAFLD was not a risk factor for the later stages of CKD.

Source link: https://doi.org/10.1371/journal.pone.0279367

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions