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Cervical Cancer - Europe PMC

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Last Updated: 19 June 2022

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The East Africa Consortium for human papillomavirus and cervical cancer in women living with HIV/AIDS.

"The East Africa Consortium was established to study human papillomavirus infections and cervical cancer, as well as the influence of human immunodeficiency virus infections on HPV and cervical cancer, as well as international collaborations between researchers in North America and East African countries," the consortium was established to investigate human papillomavirus infections and cervical cancer. These studies have provided more insight into the influence of HIV infection and cervical cancer in humans, along with the role of human immunodeficiency virus infection in HPV and cervical cancer. The East Africa Consortium was established in 1998 to investigate the epidemiology of human papillomavirus infections and cervical cancer, the effects of antiretroviral therapy on HPV and cervical cancer, as well as the differences in HPV and cervical cancer diagnosis, with either cryotherapy or LEEP.

Source link: https://europepmc.org/article/MED/35521812


Ethnographic study of the barriers and facilitators to implementing human papillomavirus (HPV) self-sampling as a primary screening strategy for cervical cancer among Inuit women of Nunavik, Northern Quebec.

"The rate of cervical cancer in Canadian Inuit women is higher than the national average. " To date, early detection remains the most effective way to minimize cervical cancer's incidence and its effects. Hence, the aim of this investigation was to investigate the barriers and facilitators in implementing human papillomavirus self-sampling as a primary screening method for cervical cancer in Inuit women of Nunavik, Northern Quebec. Participants in individual or group interviews of Nunavik's Inuit women of Nunavik were employed to determine their opinions of the barriers and facilitators to implementing HPV self-sampling as a primary screening method for cervical cancer. This report included twenty-eight Inuit women. The self-sampling process may be useful to Inuit women. The results of this research indicate that integrating the perspectives of Inuit women in implementing HPV self-sampling as a primary screening method for cervical cancer screening in Nunavik. ".

Source link: https://europepmc.org/article/MED/35166191


Brazilian Society of Surgical Oncology consensus on fertility-sparing surgery for cervical cancer.

"Objective" Several debates regarding cervical cancer treatment remain. " Methods The Brazilian Society of Surgical Oncology supported the consensus from March 2020 to September 2020, a multidisciplinary team of 55 experts. The role of less invasive involvement in radical trachelectomy and parametrial preservation was among the two areas with lower agreement rates. Conclusions: Although very few clinical trials have been conducted in cervical cancer surgery, most recommendations were backed by poor results of evidence. "Our study may have contributed to literature" on two front pages: cervical cancer conservative management was discussed in depth and innovation.

Source link: https://europepmc.org/article/MED/35689582


Construction of boric acid-functionalized metal-organic frameworks for glycopeptide recognition in the serum of cervical cancer patients.

"Rationale Cervical cancer is one of the most common malignant tumors in women, and it is important to identify potential biomarkers such as glycopeptides closely related to cancer in physiological samples of cervical cancer patients. " Methods A novel form of boric acid-functionalized MOF probe is ready to recognize glycopeptides using a post-synthesis conversion process. The results of the UiO-66@PEI@Au@B2 probe show a low detection rate, an excellent recovery rate, relatively high reusability, and selectivity compared to previous generations. When UiO-66@PEI@Au@B 2 is used to selectively capture glycopeptides from a healthy individual and a cervical cancer patient's serum, 101 glycopeptides corresponding to 54 glycoproteins and 108 glycopeptides corresponding to 57 glycoproteins are detected, respectively. UiO-66@PEI@Au@B2's excellent results not only demonstrates the uniquescent MOFs in the glycoproteome's good performance, but also opens up new phases of the use of MOF-based materials. ".

Source link: https://europepmc.org/article/MED/35445465


Hsa_circ_0084904 drives cervical cancer advancement by modulating the miR- 578/AURAK pathway

"Cervical cancer is associated with elevated incidences. " Cell proliferation, colony formation, and vitro invasion capabilities in vitro were all reduced by the hsa_circ_0084904 knockdown, according to the function assays. The effects of hsa_circ_0084904 silencing were reversed, either by AURKA overexpression or deferral. Hsa_circ_0084904 is a potential regulator of CC tumorigenesis via modulation of miR-578/AURKA axis, as well as a pharmacological potential for hsa_circ_0084904 against CC.

Source link: https://europepmc.org/article/PPR/PPR507308


Comprehensive analysis of novel prognosis-related proteomic signature effectively improve risk stratification and precision treatment for patients with cervical cancer.

"Objective Cervical cancer is one of the most common malignant female cancers, and its incidence and mortality are not encouraging. Protein panels can be a useful diagnostic indicator of many forms of cancer. The aim of our study was to investigate a proteomic panel in order to predict the survival of patients with common CC. Methods and results The protein expression and clinicopathological data of CC were downloaded from The Cancer Proteome Atlas and The Cancer Genome Atlas website, respectively. The results of functional enrichment analysis were mainly related to apoptosis, according to Univariate Cox regression analysis, which showed that the prognosis-related proteins were mainly related to apoptosis. To develop a prognostic map, we used Kaplan-Meier's report and multivariable Cox regression analysis further to screen PRPs to create a prognostic model, including BCL2, SMAD3, and 4EBP1-pT70. In addition, we investigated for the co-expressed proteins of three-protein panels as potential prognostic proteins. ".

Source link: https://europepmc.org/article/MED/35713693


Use of ginger to control nausea and vomiting caused by chemotherapy in patients with cervical cancer undergoing treatment: An experiment.

Patients with stages IB I, IB I microscopic are recommended for radiotherapy or adjuvant chemoradiotherapy with cisplatin," says the International Federation of Gynecology and Obstetrics. This research was conducted to determine the effects of ginger on chemotherapy-induced nausea and vomiting in patients of cervical cancer patients receiving cisplatin and radiotherapy. Methods and results An experimental research with a triple-blind scheme is described, comparing the benefits of institutional antiemetic therapy alone and in combination with 2 different ginger concentrations. Ethics and dissemination Due to the nature of the investigation, the Division Ethics Committee of Liga Contra o Cu00e2ncer gave us permission. The information obtained will also be available in a public repository of data. Trial registration number This study is included in the Brazilian Registry of Clinical Trials under number RBR-47yx6p9. ".

Source link: https://europepmc.org/article/MED/35713447


Estimating the turning point of the log-logistic hazard function in the presence of long-term survivors with an application for uterine cervical cancer data

"Unimodal hazard functions are present in cancer clinical trials, and it is of utmost importance to determine the turning point of hazard function," "because it is a crucial component of patient treatment decisions with cancer. " In addition, where patient cure is a possibility, estimating cure rates at various stages of cancer in lieu of their proportions may provide a more accurate picture of the effects of stages on survival rates. ".

Source link: https://europepmc.org/article/MED/PMC9041779


A comparison of behavioural models explaining cervical cancer screening uptake.

"While few studies have compared these models in terms of their ability to predict health behavior, this report examines three health behavior theories to analyze and compare CCS behavior and intention. " Methods of Data Sixteen sexually active women in the South Indian state of Karnataka conducted a survey. Logistic regression experiments investigated to what extent each of the theoretical models explained cervical cancer screening intention and regular screening behavior, comparing the differences reported by each of the models. Of the many constructs included in this report, positive attitudes toward the screening procedure and perceived benefits contributed the most to screening desire, followed by fear, anxiety, or embarrassment due to the disease or screening process, as well as contextual specific barriers. Conclusions The TPB and HBM are two of the most popular socio-cognitive factors that explains women's willingness to enroll in CCS. ".

Source link: https://europepmc.org/article/MED/35710374


Knowledge, and practice of cervical cancer prevention and associated factors among commercial sex workers in Shashemene Town, West Arsi, Oromia Region, Ethiopia.

A limited research on cervical cancer prevalence among Sex Workers in Ethiopia has been published, but a research done in Central America shows that the risk of developing HPV infection in sex workers in sex workers is 2. 5 times higher than the general population. " However, there are no studies on cervical cancer prevention among Ethiopian sexual sex workers. Methods A systematic random sampling method and an interviewer were used to investigate the prevalence and practice of cervical cancer prevention and its associated risk among 405 women of commercial sex workers with a systematic random sampling method and an interviewer. About half of respondents have information about cervical cancer, screening, and prevention, and dying, and 20. 3% of respondents were trained cervical cancer screening, while 20 percent of respondents were engaged in cervical cancer screening. Conclusions The study participants had an average awareness of cervical cancer and its prevention, but their participation was poorer than other women.

Source link: https://europepmc.org/article/MED/35710370

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions