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Cervical Cancer - ClinicalTrials.gov

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Last Updated: 19 June 2022

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Smoking Cessation for Cervical Cancer Survivors in a Safety Net Healthcare System

"Study Groups": If you decide to enroll in this study, you will be randomly assigned to one of two research groups. To eligible callers, The Quitline provides free quit smoking assistance. Saliva Testing: At Months 3, 6, 12, 18 and 18, you will also be asked to submit a saliva sample to determine your smoking status to determine your nicotine status. Telephone Counseling: If you are in Group 2, you will have 6 telephone counseling sessions that may last up to 30 minutes per session. During the calls, you'll be asked how motivated you are to quit smoking, what barriers to quitting you may have, and other things that may be related to your smoking habits, such as stress and family problems. The Length of the Study: When you complete the final questionnaire call at Month 18, your participation in the research will come to an end. If you want to leave the study early, you should notify the research workers that you do not want to participate in this research study. Demographic and Smoking History Questionnaire: You will be asked to fill a questionnaire at the time of your tour to gather demographic and smoking history data. In-depth Interview: You will be invited to talk about specific aspects of a new initiative that is designed to assist women with cervical cancer quit smoking. ".

Source link: https://clinicaltrials.gov/ct2/show/NCT02157610


Reducing Barriers and Sustaining Utilization of a Cervical Cancer Screening Program in Rural Senegal

"The aim of this report is to establish the feasibility and determinants of initial uptake and creation and tailoring a peer education health promotion strategy in Senegal's low-resource areas of cancer screening services in low-resource areas of Senegal nau00efve's cancer screening services in low-resource areas to ensure sustained utilization. " Implementation Science is the study of how proven technological solutions can be used in real world settings. In goal 2, the Integrated Theory of Health Behavior Change to determine how a peer education scheme encourages self-management of women in goal 2, and the Dynamic Sustainability Framework to assess the initial uptake and sustained use of the health service in aim 3 will be evaluated. An overview of Study Data Collection: The investigators will perform a cluster-randomized stepped wedge survey in three representative clusters in the Kedougou region to meet all objectives. Through the stepped wedge approach in the Kedougou region, the investigators will explore the creation, piloting, implementation, and adaptation of an aim-informed multi-level peer education curriculum across clusters. At any time period, the investigators will collect quantitative program reach results and qualitative process evaluation data. The investigators will gather aggregated health service level utilization data and individual surveys to achieve goal 3.

Source link: https://clinicaltrials.gov/ct2/show/NCT03540069


Randomized Controlled Trial of an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya

"Specific Aims Seven percent of cervical cancer deaths worldwide occur in low and middle-income countries, and cervical cancer is the most common disease in sub-Saharan Africa. " Although nearly 89% of women in the United States receive cervical cancer screening, only about 5% of women in LMICs have been screened. Women account for 59% of all people living with HIV and cervical cancer deaths, though cervical cancer incidence in women with HIV is on the rise. Women receiving HIV treatment have an increased life expectancy following that of HIV-negative women with the introduction of antiretroviral therapy. Despite ART and immune reconstitution, cervical cancer rates do not significantly decline, though stem and immune reconstitution have increased, and invasive cervical cancer incidence remains high even with ART. In a cluster randomized trial in 20 FP clinics in Mombasa County, AIM 2: To determine whether SAIA enhances cervical cancer screening compared to normal procedures. HYP 2: Family planning clinics that were randomly assigned to SAIA will see increased rates of cervical cancer screening by reducing bottlenecks in screening procedures relative to clinics that were not randomized to standard procedures. AIM 3: To determine the cost and budget implications of using SAIA to increase cervical cancer screening in FP clinics in Mombasa County. Expected Outputs and Public Health Impact As one of African women's most prevalent causes of cancer deaths, immediate care must be paid to raise rates of cervical cancer screening and treatment of pre-cancerts is vital. ".

Source link: https://clinicaltrials.gov/ct2/show/NCT03514459


UNCPM 21904 - Prevention of Cervical Cancer Through an HPV-based Screen-and-treat Strategy in Malawi: a Cluster Randomized Trial

"This is a cluster randomised trial that will integrate a novel cervical cancer screen-and-treat algorithm into voluntary family planning services using two distinct strategies aimed at lowering barriers to screening and treatment in resource poor settings. " If your hr-HPV test is positive, they will be able to perform cervico-vaginal self-sampling in the community via Heath Surveillance Assistants HSAs, but they will also be able to perform cervico-vaginal self-sampling in the community, allowing them to return to the clinic for VIA and potential same-day thermocoagulation if their hr-HV test is positive. The project's primary aim is to determine the availability and affordability of these two models for averting future cervical cancer cases and determining their acceptance and acceptability in a variety of health care facility settings. This survey will ask questions regarding basic demographic data, reproductive health information, HIV status, proximity to the nearest health facility, prior VFP use, prior cervical cancer screening and preventive therapy CCSPT services provided, and any CCSPT services provided during project implementation. ".

Source link: https://clinicaltrials.gov/ct2/show/NCT04286243


Clinical Performance Validation of Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa

"Invasive cervical cancer is a significant health problem in low and middle-income countries. " HIV-infected women in Africa are particularly vulnerable, and their estimated invasive cervical cancer risk is a 20-fold greater risk than those without HIV. Previous studies were only designed for HIV-infected women or those whose HIV status was unclear. In addition, HIV-infected women are often diagnosed with invasive cervical cancer at younger ages. In both high and low resource settings, the World Health Organisation recently recommends high risk HPV testing for cervical cancer screening. The study shows that high-risk human papillomavirus testing on urine samples will be similar in sensitivity and specificity for the detection of cervical intra-epithelial neoplasia grade 2 or worse in comparison to self- or clinician-collected samples. This research will explore whether women can obtain their own samples for HPV testing using either urine or a small bush in the vagina.

Source link: https://clinicaltrials.gov/ct2/show/NCT05413798


Application of Intermittent Catheterization in Patients With Micturition Dysfunction After Postoperative Radiotherapy for Cervical Cancer

As the research objectives, patients with postoperative radiotherapy for cervical cancer patients with voiding dysfunction were identified in this report. " At the start of the study, a total of 80 people were randomly divided into two groups: 40 cases in the observation group and 40 in the control group were randomly divided into two groups: 40 cases in the observation group and 40 in the control group were randomly divided into two groups: 40 cases in the observation group and 40 in the control group. For three meals in the morning, noon, and evening, the water intake for three meals is 400 milll respectively, and about 200 million water is taken between meals. For dinner, 200ml water is taken 2 hours after dinner, no water is consumed 2-3 hours before going to bed, and no water is taken 2-3 hours before going to bed. The residual urine volume, which is determined by the derived urine volume, is the residual urine volume. Patients or their families can talk to patients or their families to answer patient inquiries and solve operational issues at any time; patients can go to www. british. com/content. Patients can drink and urination diaries every day; for three days after the introduction of intermittent catheterization, patients can be able to answer patients' questions and solve operational problems at any time; For three days after the introduction of intermittent catheterization, patients can be referred to. If the patient's remaining urine volume is less than 100 millil or less than 20% of the normal bladder capacity for three days in a row, it is presumed that the bladder function has been restored and intermittent catheterization can be stopped. Every 7 days until the end of radiotherapy, the bladder function of the observation group and the control group was tested during radiotherapy.

Source link: https://clinicaltrials.gov/ct2/show/NCT05410444


A Randomized Phase III Study of Standard vs. IMRT Pelvic Radiation for Post-Operative Treatment of Endometrial and Cervical Cancer (TIME-C)

"OBJECTIVES: Primary In the 5th week of pelvic radiation therapy as measured with the expanded prostate cancer index composite device, it was determined that pelvic intensity-modulated radiation therapy reduces acute gastrotoxicity. " Secondary To find out if grade 2+ gastrointestinal toxicity is reduced by IMRT relative to conventional whole-pelvis radiation therapy, it's also determined when grade 2+ gastrointestinal toxicity is reduced with IMRT relative to whole-pelvis radiation therapy. Using the EPIC urinary domain, we can determine if urinary toxicity is reduced with IMRT. In women undergoing either IMRT pelvic radiation therapy or four-field pelvic radiation therapy for endometrial or cervical cancer, we found EPIC bowel and urinary domains. Using the Functional Assessment of Cancer Therapy-General with cervix subscale, we can determine the effects of pelvic IMRT on quality of life. Arm I: Patients receive standard radiation therapy 5 days a week for up to 5 weeks. On day 1, some patients receive cisplatin IV over a 1-hour course. ".

Source link: https://clinicaltrials.gov/ct2/show/NCT01672892


Promoting Comprehensive Cervical Cancer Prevention and Better Women's Health in Low- and Medium Resource Settings HPV Screening With Triage by HPV Genotyping Versus Visual Inspection With Acetic Acid: a Randomized Controlled Trial

"Triage by HPV genotyping has recently emerged as an alternative to triage by VIA, with immediate care of women with a subset of high-risk HPV genotypes exclusively, thereby lowering overtreatment rates. " u00a8: Secondary objectives: To determine the prevalence of cervical cancer, sexually transmitted diseases, and HIV among all screening groups, as well as general educational screening The aim of this study period is to determine whether or not the screening process and treatment will continue to progress. To determine whether cervical precancerous lesions could be related to improved screening results and outcomes.

Source link: https://clinicaltrials.gov/ct2/show/NCT05385406

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions