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Both morbidity and mortality in both morbidity and mortality, where both innate and adaptive immune responses play a vital role in the pathogenesis of TBI. However, the role of gamma-delta T cells in acute and chronic TBI is uncertain. Here, we find that u03b3u03b4 T cells influence TBI's pathophysiology as early as one day and up to one year after injury. These results reveal new insights into the role of various u03b3u03b4 cell subsets after brain injury, resulting in novel avenues for the development of targeted u03b3r-based therapy for TBI.
Source link: https://europepmc.org/article/PPR/PPR539507
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