Cell (Novel) - DOAJ

Pathways of Glucagon Secretion and Trafficking in the Pancreatic Alpha Cell: Novel Pathways, Proteins, and Targets for Hyperglucagonemia

Hyperglucagonemia may be triggered by defective alpha cell secretory responses to glucose and paracrine effectsors in both Type 1 and Type 2 diabetes. We'll focus on alpha cell dysfunction in diabetes, intrinsic and paracrine control of glucagon secretion, undercover and paracrine measurements of granule dynamics, and changes in intracellular trafficking in this report.

Source link: https://doi.org/10.3389/fendo.2021.726368

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